Albrecht Jennifer S, Peters Matthew E, Smith Gordon S, Rao Vani
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Drs Albrecht and Smith); Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Drs Peters and Rao); and Shock, Trauma and Anesthesiology Research-Organized Research Center, National Study Center for Trauma and Emergency Medical Services, University of Maryland, College Park (Dr Smith).
J Head Trauma Rehabil. 2017 May/Jun;32(3):178-184. doi: 10.1097/HTR.0000000000000266.
To estimate rates of anxiety and posttraumatic stress disorder (PTSD) diagnoses after traumatic brain injury (TBI) among Medicare beneficiaries, quantify the increase in rates relative to the pre-TBI period, and identify risk factors for diagnosis of anxiety and PTSD.
A total of 96 881 Medicare beneficiaries hospitalized with TBI between June 1, 2006 and May 31, 2010.
Retrospective cohort study.
Diagnosis of anxiety (International Classification of Diseases, Ninth Revision, Clinical Modification [ICD-9-CM] codes 300.0x) and/or PTSD (ICD-9-CM code 309.81).
After TBI, 16 519 (17%) beneficiaries were diagnosed with anxiety and 269 (0.3%) were diagnosed with PTSD. Rates of anxiety and PTSD diagnoses were highest in the first 5 months post-TBI and decreased over time. Pre-TBI diagnosis of anxiety disorder was significantly associated with post-TBI anxiety (risk ratio, 3.55; 95% confidence interval, 3.42-3.68) and pre-TBI diagnosis of PTSD was significantly associated with post-TBI PTSD (risk ratio 70.09; 95% confidence interval 56.29-111.12).
This study highlights the increased risk of anxiety and PTSD after TBI. Routine screening for anxiety and PTSD, especially during the first 5 months after TBI, may help clinicians identify these important and treatable conditions, especially among patients with a history of psychiatric illness.
评估医疗保险受益人中创伤性脑损伤(TBI)后焦虑症和创伤后应激障碍(PTSD)的诊断率,量化相对于TBI前时期诊断率的增加情况,并确定焦虑症和PTSD诊断的危险因素。
2006年6月1日至2010年5月31日期间因TBI住院的96881名医疗保险受益人。
回顾性队列研究。
焦虑症诊断(《国际疾病分类,第九版,临床修订本》[ICD-9-CM]编码300.0x)和/或PTSD(ICD-9-CM编码309.81)。
TBI后,16519名(17%)受益人被诊断为焦虑症,269名(0.3%)被诊断为PTSD。焦虑症和PTSD的诊断率在TBI后的前5个月最高,并随时间下降。TBI前焦虑症诊断与TBI后焦虑症显著相关(风险比,3.55;95%置信区间,3.42 - 3.68),TBI前PTSD诊断与TBI后PTSD显著相关(风险比70.09;95%置信区间56.29 - 111.12)。
本研究强调了TBI后焦虑症和PTSD风险增加。对焦虑症和PTSD进行常规筛查,尤其是在TBI后的前5个月,可能有助于临床医生识别这些重要且可治疗的病症,特别是在有精神疾病史的患者中。