Department of Chemistry, University of Connecticut, Storrs, CT.
Photochem Photobiol. 2017 Oct;93(5):1320-1325. doi: 10.1111/php.12787. Epub 2017 Jul 27.
The tolyporphins, a family of green tetrapyrrolic pigments isolated from a cyanobacterium-microbial ecological unit, possess unique carbohydrate-derivatized dioxobacteriochlorin frameworks. A brief overview over the history, synthesis, chemistry and biological properties of the tolyporphins forms the backdrop for highlighting the contribution by Hood et al. (Photochem. Photobiol., 2017, https://doi.org/10.1111/php.12781) who demonstrate the optical properties of tolyporphins to be more similar to those of chlorins than of bacteriochlorins. This property could be correlated with the presence of β-oxo-functionalities. The study continues to clarify the structure, properties and possible roles of these intriguing chromophores with a range of biomedical properties.
从蓝细菌-微生物生态单元中分离出的一类绿色四吡咯色素——托利卟啉，具有独特的碳水化合物衍生二酮菌绿素骨架。本文简要概述了托利卟啉的历史、合成、化学和生物学特性，突出了 Hood 等人的贡献（Photochem. Photobiol.，2017，https://doi.org/10.1111/php.12781），他们证明托利卟啉的光学性质与类菌绿素相比更类似于叶绿素。这一性质可能与β-氧官能团的存在有关。该研究继续阐明这些具有多种生物医学特性的迷人生色团的结构、性质和可能作用。
