采用新方法评估多种因素对非综合征性单侧唇腭裂患儿牙弓关系的影响:一项回顾性研究
The effect of various factors on the dental arch relationship in non-syndromic unilateral cleft lip and palate children assessed by new approach: a retrospective study.
作者信息
Haque Sanjida, Alam Mohammad Khursheed, Khamis Mohd Fadhli
机构信息
Orthodontic Unit, School of Dental Science, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Orthodontic Department, College of Dentistry, Al Jouf University, Sakaka, Kingdom of Saudi Arabia.
出版信息
BMC Pediatr. 2017 May 6;17(1):119. doi: 10.1186/s12887-017-0870-4.
BACKGROUND
Cleft lip and palate (CLP) is one of the most common birth defects. Multiple factors are believed to be responsible for an unfavorable dental arch relationship in CLP. Facial growth (maxillary) retardation, which results in class III malocclusion, is the primary challenge that CLP patients face. Phenotype factors and postnatal treatment factors influence treatment outcomes in unilateral cleft lip and palate (UCLP) children, which has led to a great diversity in protocols and surgical techniques by various cleft groups worldwide. The aim of this study was to illustrate the dental arch relationship (DAR) and palatal morphology (PM) of UCLP in Bangladeshi children and to explore the various factors that are responsible for poor DAR and PM.
METHODS
Dental models of 84 subjects were taken before orthodontic treatment and alveolar bone grafting. The mean age was 7.69 (SD 2.46) years. The DAR and PM were assessed blindly by five raters using the EUROCRAN index (EI). Kappa statistics was used to evaluate the intra- and inter-examiner agreement, chi square was used to assess the associations, and logistic regression analysis was used to explore the responsible factors that affect DAR and PM.
RESULTS
The mean EUROCRAN scores were 2.44 and 1.93 for DAR and PM, respectively. Intra- and inter-examiner agreement was moderate to very good. Using crude and stepwise backward regression analyses, significant associations were found between the modified Millard technique (P = 0.047, P = 0.034 respectively) of cheiloplasty and unfavorable DAR. Complete UCLP (P = 0.017) was also significantly correlated with unfavorable DAR. The PM showed a significant association with the type of cleft, type of cheiloplasty and type of palatoplasty.
CONCLUSION
This multivariate study determined that the complete type of UCLP and the modified Millard technique of cheiloplasty had significantly unfavorable effects on both the DAR and PM.
背景
唇腭裂(CLP)是最常见的出生缺陷之一。多种因素被认为与唇腭裂患者不良的牙弓关系有关。导致Ⅲ类错牙合的面部生长(上颌骨)迟缓是唇腭裂患者面临的主要挑战。表型因素和产后治疗因素会影响单侧唇腭裂(UCLP)儿童的治疗效果,这导致全球各腭裂治疗团队在治疗方案和手术技术上存在很大差异。本研究的目的是阐明孟加拉国儿童单侧唇腭裂的牙弓关系(DAR)和腭部形态(PM),并探讨导致不良牙弓关系和腭部形态的各种因素。
方法
在正畸治疗和牙槽骨植骨前,获取了84名受试者的牙模。平均年龄为7.69岁(标准差2.46)。由五名评估者使用EUROCRAN指数(EI)对牙弓关系和腭部形态进行盲法评估。kappa统计用于评估检查者内部和检查者之间的一致性,卡方检验用于评估相关性,逻辑回归分析用于探讨影响牙弓关系和腭部形态的相关因素。
结果
牙弓关系和腭部形态的EUROCRAN平均得分分别为2.44和1.93。检查者内部和检查者之间的一致性为中等至非常好。通过单因素和逐步向后回归分析发现,唇裂修复术的改良Millard技术(分别为P = 0.047,P = 0.034)与不良牙弓关系之间存在显著相关性。完全性单侧唇腭裂(P = 0.017)也与不良牙弓关系显著相关。腭部形态与腭裂类型、唇裂修复术类型和腭裂修复术类型之间存在显著关联。
结论
这项多变量研究确定,完全性单侧唇腭裂类型和改良Millard唇裂修复术对牙弓关系和腭部形态均有显著不利影响。