Defabianis Patrizia, Guagnano Rosa, Romano Federica
Department of Surgical Sciences, C.I.R. Dental School, University of Turin, 10126 Turin, Italy.
Private Practice, 10100 Turin, Italy.
Children (Basel). 2023 Sep 15;10(9):1559. doi: 10.3390/children10091559.
Dental arch relationships (DARs) and palatal morphology (PM) were evaluated in in non-syndromic complete unilateral cleft lip and palate (UCLP) Italian patients after surgery. Pre- and postnatal factors affecting the results were investigated. Sixty-six children with UCLP (40 boys and 26 girls, with a mean age of 10.1 ± 2.9 years), predominantly Caucasian (77%), were consecutively enrolled in this cross-sectional study. Twenty children had received a one-stage protocol consisting of an early periosteal palate surgical repair and lip closure and forty-six were submitted to a staged surgical protocol with delayed palate repair (DPR). A single clinician collected data on their medical history and carried out a dental examination. The DAR and PM were graded on dental casts according to the Eurocran index and dichotomised as favourable and unfavourable based on the treatment outcome. Multiple logistic regression analyses demonstrated that female sex (OR = 6.08, 95% CI: 1.47-25.23, = 0.013), DPR (OR = 4.77, 95% CI: 1.14-19.93, = 0.032) and the use of a neonatal plate (OR = 4.68, 95% CI: 1.27-17.16, = 0.020) increased the odds of having favourable DAR, while only DPR (OR = 9.76, 95% CI: 2.40-39.71, = 0.001) was significantly associated with a favourable PM. Based on these findings, only DPR had a significantly favourable effect on both DAR and DM in Italian children with complete UCLP.
对意大利非综合征性完全性单侧唇腭裂(UCLP)患者术后的牙弓关系(DARs)和腭部形态(PM)进行了评估。研究了影响结果的产前和产后因素。66例UCLP儿童(40名男孩和26名女孩,平均年龄10.1±2.9岁),主要为白种人(77%),连续纳入本横断面研究。20名儿童接受了包括早期骨膜腭裂手术修复和唇裂修复的一期治疗方案,46名儿童接受了延迟腭裂修复(DPR)的分期手术方案。由一名临床医生收集他们的病史数据并进行牙科检查。根据Eurocran指数对石膏模型上的DAR和PM进行分级,并根据治疗结果分为有利和不利两类。多因素logistic回归分析表明,女性(OR = 6.08,95%CI:1.47 - 25.23,P = 0.013)、DPR(OR = 4.77,95%CI:1.14 - 19.93,P = 0.032)和使用新生儿腭托(OR = 4.68,95%CI:1.27 - 17.16,P = 0.020)增加了获得有利DAR的几率,而只有DPR(OR = 9.76,95%CI:2.40 - 39.71,P = 0.001)与有利的PM显著相关。基于这些发现,在意大利完全性UCLP儿童中,只有DPR对DAR和PM均有显著的有利影响。