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早产的长期影响:神经发育和身体健康结果

Long-Term Impact of Preterm Birth: Neurodevelopmental and Physical Health Outcomes.

作者信息

Luu Thuy Mai, Rehman Mian Muhammad Oneeb, Nuyt Anne Monique

机构信息

Department of Pediatrics, Research Center, Centre Hospitalier Universitaire Sainte-Justine, 3175 Côte-Ste-Catherine, Montreal, Quebec H3T 1C5, Canada.

Department of Biomedical Sciences, Fetomaternal and Neonatal Pathologies Axis, Research Center, Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, 3175 Côte-Ste-Catherine, Montreal, Quebec H3T 1C5, Canada.

出版信息

Clin Perinatol. 2017 Jun;44(2):305-314. doi: 10.1016/j.clp.2017.01.003. Epub 2017 Mar 18.

DOI:10.1016/j.clp.2017.01.003
PMID:28477662
Abstract

Preterm birth severely disrupts the normal developmental maturation of organ systems, resulting in lasting adverse effects. High blood pressure, cardiac dysfunction, obstructive lung disease, elevated blood glucose, and mental health problems occur earlier and at higher rates in the preterm-born than in the term populations. Disadvantageous health conditions may have a significant impact on the well-being of preterm-born individuals from childhood through adulthood. This review summarizes the impact of preterm birth on neurodevelopment and on cardiovascular, renal, metabolic, and pulmonary health.

摘要

早产会严重扰乱器官系统的正常发育成熟,从而产生持久的不良影响。与足月儿相比,早产儿患高血压、心脏功能障碍、阻塞性肺病、血糖升高和心理健康问题的时间更早,发生率更高。不利的健康状况可能会对早产儿从童年到成年的幸福产生重大影响。这篇综述总结了早产对神经发育以及心血管、肾脏、代谢和肺部健康的影响。

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