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可存活孕周前出生的流行病学:双胎妊娠的影响及新生儿结局

Epidemiology of Periviable Births: The Impact and Neonatal Outcomes of Twin Pregnancy.

作者信息

Ananth Cande V, Chauhan Suneet P

机构信息

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, 622 West 168 Street, New York, NY 10032, USA; Department of Epidemiology, Joseph L. Mailman School of Public Health, Columbia University, 722 West 168 Street, New York, NY 10032, USA.

Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, University of Texas, 6432 Fannin Street, MSB 3.286, Houston, TX 77030, USA.

出版信息

Clin Perinatol. 2017 Jun;44(2):333-345. doi: 10.1016/j.clp.2017.01.002. Epub 2017 Mar 11.

DOI:10.1016/j.clp.2017.01.002
PMID:28477664
Abstract

This article discusses a study that estimated the prevalence of twin live births in the United States that were delivered in the periviable (20-25 weeks) gestational age, and compared changes in twin neonatal mortality and morbidity rates between 2005 and 2013 overall, and at periviable gestations. Although the decline in twin neonatal mortality rates at 23 and 24 weeks is encouraging, and suggests advancement in the neonatal care of these extremely small twins, the concomitant increase in neonatal morbidity at 23 weeks is concerning. Efforts to understand if twins delivered at periviable gestations suffer from long-term consequences of neurodevelopmental and cognitive deficits remain important.

摘要

本文讨论了一项研究,该研究估算了在美国孕周为20至25周的可存活孕周时分娩的双胎活产的患病率,并比较了2005年至2013年期间总体以及可存活孕周时双胎新生儿死亡率和发病率的变化。尽管23周和24周时双胎新生儿死亡率的下降令人鼓舞,并表明这些极小的双胎在新生儿护理方面取得了进展,但23周时新生儿发病率的相应增加令人担忧。了解在可存活孕周分娩的双胎是否患有神经发育和认知缺陷的长期后果的努力仍然很重要。

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