Varin Mélanie, Charbotel Barbara, Pérol Olivia, Perrier Lionel, Massardier-Pilonchéry Amélie, Bonnand Sandrine, Belladame Elodie, Fort Emmanuel, Avrillon Virginie, Rebattu Paul, Pérol Maurice, Fervers Béatrice
Université Lyon, université Lyon 1, IFSTTAR, UMRESTTE, UMR_T9405, 69373 Lyon, France.
Université Lyon, université Lyon 1, IFSTTAR, UMRESTTE, UMR_T9405, 69373 Lyon, France; Centre Léon-Bérard, département cancer et environnement, 28, rue Laënnec, 69373 Lyon cedex 08, France; Hospices civils de Lyon, centre hospitalier Lyon Sud, service de pathologies professionnelles, 69495 Pierre- Bénite, France.
Bull Cancer. 2017 Jun;104(6):559-564. doi: 10.1016/j.bulcan.2017.03.014. Epub 2017 May 3.
Ten to 29% of lung cancers might be linked to occupational factors but 60% of them are not compensated. The PROPOUMON project aimed to improve the identification, recognition and compensation of occupational lung cancer as occupational disease using a self-administered questionnaire (AQREP). One objective was to assess the AQREP, comparing it with the questionnaire drawn up by the French Language Pneumology Society (Q-SPLF). From March 2014 to September 2015, 90 lung cancer patients treated at the Centre Léon-Bérard responded to the AQREP and Q-SPLF. The two physicians in charge of the consultation assessed independently whether or not a consultation was indicated. A certificate for the compensation process was proposed when a suspicion of high or average imputability was identified. Analysis of the questionnaires was concordant for 73% of the patients. The AQREP has a sensitivity of 72% and a specificity of 73%. Its positive and negative predictive values were 62 and 82%. The information provided by 24 patients were discordant between questionnaires. In two patients with discordant evaluation (AQREP+/Q-SPLF-; AQREP-/Q-SPLF+), one Initial Medical Certificate (IMC) was written. This study made it possible to conclude that AQREP is relevant for the identification of potentially occupational lung cancers. Collegial discussion of complex cases might be considered. The project is currently been extended to other centers and to lymphoma.
10%至29%的肺癌可能与职业因素有关，但其中60%未得到赔偿。PROPOUMON项目旨在通过一份自填式问卷（AQREP）来改善职业性肺癌作为职业病的识别、认定和赔偿。一个目标是评估AQREP，并将其与法国语言肺科学会制定的问卷（Q-SPLF）进行比较。2014年3月至2015年9月，在里昂贝拉尔中心接受治疗的90名肺癌患者对AQREP和Q-SPLF进行了回应。负责会诊的两名医生独立评估是否需要会诊。当确定存在高度或中度可归责性怀疑时，会提出赔偿程序证书。对73%的患者问卷分析结果一致。AQREP的敏感性为72%，特异性为73%。其阳性和阴性预测值分别为62%和82%。24名患者在两份问卷中提供的信息不一致。在两名评估结果不一致的患者中（AQREP+/Q-SPLF-；AQREP-/Q-SPLF+），撰写了一份初始医疗证明（IMC）。这项研究得出结论，AQREP对于识别潜在的职业性肺癌是相关的。可以考虑对复杂病例进行合议讨论。该项目目前正在扩展到其他中心以及淋巴瘤。
