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用于治疗脊柱肿瘤的可透射线碳纤维增强椎弓根螺钉:对放射治疗计划和随访成像的优势

Radiolucent Carbon Fiber-Reinforced Pedicle Screws for Treatment of Spinal Tumors: Advantages for Radiation Planning and Follow-Up Imaging.

作者信息

Ringel Florian, Ryang Yu-Mi, Kirschke Jan S, Müller Birgit S, Wilkens Jan J, Brodard Jeremy, Combs Stephanie E, Meyer Bernhard

机构信息

Department of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Department of Neurosurgery, University of Mainz, Mainz, Germany.

Department of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

出版信息

World Neurosurg. 2017 Sep;105:294-301. doi: 10.1016/j.wneu.2017.04.091. Epub 2017 May 3.

Abstract

OBJECTIVE

Surgical treatment of spinal tumors regularly includes spinal instrumentation with pedicle screws. Most modern pedicle screws are made of titanium alloy, which is associated with artifacts on postoperative imaging such as computed tomography and/or magnetic resonance imaging. These artifacts hamper radiation treatment planning and execution and follow-up imaging. Recently, carbon fiber-reinforced polyetheretherketone (CFRP) implants became available for posterior instrumentation with the aim to reduce imaging artifacts by implants.

METHODS

Patients harboring spinal tumors underwent posterior stabilization using CFRP pedicle screws. Postoperative imaging was evaluated for implant artifacts. Radiation planning was assessed.

RESULTS

Thirty-five patients with spinal tumors were assessed (metastases n = 30; lymphoma n = 2, myeloma n = 1, chordoma n = 1, fibrous dysplasia n = 1). Implantation of CFRP implants was feasible in all but 1 case. Postoperative images show reduced artifacts in comparison with standard titanium alloy implants. Implant position and integrity is sufficiently assessable despite reduced image contrast. Radiation planning is improved.

CONCLUSIONS

Carbon fiber-reinforced PEEK pedicle screws reduce image artifacts on computed tomography and magnetic resonance imaging. Thereby, they are a valuable and feasible option for spinal instrumentations in patients harboring spinal tumors where postoperative imaging and radiation therapy planning are necessary and might be crucial for long-term outcome and overall survival.

摘要

目的

脊柱肿瘤的手术治疗通常包括使用椎弓根螺钉进行脊柱内固定。大多数现代椎弓根螺钉由钛合金制成,这会在术后成像(如计算机断层扫描和/或磁共振成像)上产生伪影。这些伪影会妨碍放射治疗计划的制定与实施以及后续成像。最近,碳纤维增强聚醚醚酮(CFRP)植入物可用于后路内固定,旨在减少植入物产生的成像伪影。

方法

患有脊柱肿瘤的患者使用CFRP椎弓根螺钉进行后路稳定手术。对术后成像的植入物伪影进行评估。评估放射治疗计划。

结果

评估了35例脊柱肿瘤患者(转移瘤30例;淋巴瘤2例,骨髓瘤1例,脊索瘤1例,骨纤维异常增殖症1例)。除1例病例外,CFRP植入物的植入在所有病例中均可行。与标准钛合金植入物相比,术后图像显示伪影减少。尽管图像对比度降低,但植入物位置和完整性仍可充分评估。放射治疗计划得到改善。

结论

碳纤维增强聚醚醚酮椎弓根螺钉可减少计算机断层扫描和磁共振成像上的图像伪影。因此,对于需要进行术后成像和放射治疗计划且这可能对长期预后和总生存期至关重要的脊柱肿瘤患者,它们是脊柱内固定的一种有价值且可行的选择。

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