National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; Department of Orthopaedics, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, China.
National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Int J Surg. 2017 Jun;42:110-116. doi: 10.1016/j.ijsu.2017.04.064. Epub 2017 May 3.
Management of bone defects caused by trauma, osteomyelitis, and tumors is challenging, with many controversies over the optimal reconstruction method. Masquelet discovered induced membrane in management of large diaphyseal defects accidentally, and developed this technique with a concept of induced membrane. Induced membrane technique holds great potential for the reconstruction of bone defects, alternatively to manage this clinical challenge quiet easily. Induced membrane has unique structural characteristics and biological properties, which render this technique has an advantage of the time to bone healing is relatively independent of the length of bone defect. Herein, we reviewed the latest advances made in induced membrane technique and highlighted the concept of induced membrane in the management of bone defects.
创伤、骨髓炎和肿瘤引起的骨缺损的治疗具有挑战性，对于最佳的重建方法存在许多争议。Masquelet 意外地在大骨干缺损的治疗中发现诱导膜，并在诱导膜概念的基础上发展了这项技术。诱导膜技术为骨缺损的重建提供了很大的潜力，可替代地轻松应对这一临床挑战。诱导膜具有独特的结构特征和生物学特性，使该技术在骨愈合时间上相对独立于骨缺损的长度。在此，我们综述了诱导膜技术的最新进展，并强调了诱导膜在骨缺损治疗中的概念。
