Schattenberg A, De Vries F, De Witte T, Cohen O, Donnelly J P, De Pauw B E
University Hospital Nijmegen, The Netherlands.
Bone Marrow Transplant. 1988 Sep;3(5):509-12.
A patient with acute myeloid leukemia (AML) who developed probable aspergillosis of the lung underwent partial lobectomy prior to allogeneic bone marrow transplantation (BMT). Diagnosis was proven by microscopic examination of the resected lung tissue. Local and systemic antifungal prophylaxis with oral amphotericin B plus itraconazole was given throughout the immediate post-transplant period and there was no evidence of recurrent mycosis. Fourteen months after BMT the patient is well, in complete remission and leading a normal life. Pre-transplant pulmonary aspergillosis need not therefore be a contraindication to successful BMT.
一名患有急性髓细胞白血病（AML）且可能发生肺部曲霉病的患者在进行异基因骨髓移植（BMT）之前接受了部分肺叶切除术。通过对切除的肺组织进行显微镜检查证实了诊断。在移植后的整个急性期给予口服两性霉素B加伊曲康唑进行局部和全身抗真菌预防，且没有复发性真菌病的证据。骨髓移植后14个月，患者情况良好，处于完全缓解状态，过着正常生活。因此，移植前的肺部曲霉病不一定是成功进行骨髓移植的禁忌症。
