Sabaté-Llobera A, Cortés-Romera M, Gamundí-Grimalt E, Sánchez-Fernández J J, Rodríguez-Bel L, Gámez-Cenzano C
PET Unit, Department of Nuclear Medicine - IDI, Hospital Universitari de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
PET Unit, Department of Nuclear Medicine - IDI, Hospital Universitari de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
Rev Esp Med Nucl Imagen Mol. 2017 Nov-Dec;36(6):396-398. doi: 10.1016/j.remn.2017.02.010. Epub 2017 May 4.
An imaging case is presented on a patient referred to our department for an F-FDG-PET/CT, as a paraneoplastic syndrome was suspected due to his clinical situation. He had a history of acute myeloid leukemia (AML) treated two years earlier, with sustained complete remission to date. F-FDG-PET/CT findings revealed hypermetabolism in almost all nerve roots, suggesting meningeal spread, consistent with the subsequent MRI findings. Cerebrospinal fluid (CSF) findings confirmed a leptomeningeal reactivation of AML. Although not many studies have evaluated the role of F-FDG-PET/CT in leukemia, it is a noninvasive tool for detecting extramedullary sites of disease and a good imaging alternative for those patients on whom an MRI cannot be performed.
本文介绍了一例影像学病例。该患者因临床情况疑似副肿瘤综合征，被转诊至我科进行F-FDG-PET/CT检查。他有急性髓系白血病（AML）病史，两年前接受过治疗，至今维持完全缓解状态。F-FDG-PET/CT检查结果显示几乎所有神经根均有代谢增高，提示脑膜播散，这与随后的MRI检查结果一致。脑脊液（CSF）检查结果证实为AML软脑膜复发。尽管评估F-FDG-PET/CT在白血病中作用的研究不多，但它是一种检测髓外疾病部位的非侵入性工具，对于无法进行MRI检查的患者是一种很好的影像学选择。
