Reis Elizabeth, McCarthy Matthew W
Perspect Biol Med. 2016;59(3):391-398. doi: 10.1353/pbm.2016.0033.
An intersex condition is one in which an individual is born with atypical male or female external genitalia, gonads, hormones, or chromosomes. Older terms, such as pseudohermaphroditism and hermaphroditism, are controversial, leading the Lawson Wilkins Pediatric Endocrine Society (LWPES) and the European Society for Paediatric Endocrinology (ESPE) to propose in 2006 the expression "disorders of sex development" (DSD), a contentious term in its own right, to define congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical. The birth of a child with DSD often prompts a long-term, multidisciplinary strategy, involving an array of health-care professionals. While much has been written about these potentially challenging management decisions, particularly those regarding infant genital surgery, very little has been written on the health management of intersex adults, and no literature exists regarding the role of the hospitalists-specialists in inpatient medicine-in the care of patients with DSD. With more than 50,000 members, Hospital Medicine represents the fast-growing subspecialty in the history of medicine. We believe hospitalists are uniquely positioned to provide high-quality care while educating trainees about issues pertinent to this often marginalized patient population. This essay poses a case study to explore some of the medical issues that intersex patients face as adults and that hospitalists will likely encounter.
间性状况是指个体出生时具有非典型的男性或女性外生殖器、性腺、激素或染色体。诸如假两性畸形和两性畸形等旧术语存在争议,这导致劳森·威尔金斯儿科内分泌学会(LWPES)和欧洲儿科内分泌学会(ESPE)在2006年提出了“性发育障碍”(DSD)这一表述——其本身也是一个有争议的术语——来定义染色体、性腺或解剖学性别的发育不典型的先天性疾病。患有DSD的儿童出生往往会促使采取一项长期的多学科策略,涉及一系列医疗保健专业人员。虽然已经有很多关于这些可能具有挑战性的管理决策的文章,尤其是那些关于婴儿生殖器手术的决策,但关于间性成年人的健康管理的文章却很少,而且不存在关于住院医师(内科住院专科医生)在照顾DSD患者中所起作用的文献。《医院医学》拥有超过5万名会员,代表了医学史上快速发展的亚专业。我们认为住院医师处于独特的地位,能够在为实习生提供与这个经常被边缘化的患者群体相关的问题的教育的同时,提供高质量的护理。本文提出一个案例研究,以探讨间性患者成年后面临的一些医学问题以及住院医师可能会遇到的问题。