Muoneke V U, Una A F, Eke C B, Anyanwu O U
Department of Pediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Department of Community Medicine, Federal Teaching Hospital, Abakaliki, Ebonyi, Nigeria.
Ann Med Health Sci Res. 2016 Jul-Aug;6(4):243-250. doi: 10.4103/amhsr.amhsr_342_14.
Renal diseases are important causes of morbidity and mortality in children worldwide particularly in the resource-poor countries of sub-Saharan Africa. Adequate data on these diseases in children in our setting are limited as a result of late/nonpresentation.
The aim of the study is to review the pattern and outcome of pediatric renal admissions at the Federal Teaching Hospital (FETH) Abakaliki over a 3-year period.
This was a retrospective observational review of all childhood renal admissions in FETH, Abakaliki, Ebonyi state between 2011 and 2013. Relevant clinical data extracted from the hospital records included patients' biodata, presenting symptom(s), examination finding (s), laboratory investigation results as well as treatment and outcome using a semi-structured questionnaire. Data collected were analyzed using SPSS software package version 16.0. The differences in proportions were tested for statistical significance using the Chi-square statistics. Statistical significance was based on < 0.05.
In the period under review, 1780 children were admitted, of which 4.4% (79/1780) had renal disorders. The mean age of the children was 8.37 (5.1) years. Nephrotic syndrome 32.9% (26/79) was the most common while on individual basis, meatal stenosis, acute kidney injury and end-stage renal disease, respectively, 1.3% (1/79) were the least renal disorders in the study population. The association between treatment mode and outcome of the treatment was statistically significant ( = 0.03), whereas other variables, such as age ( = 0.42), sex ( = 0.28), socioeconomic status ( = 0.33), and type of renal disease ( = 1.00) were not statistically significant. The case fatality rate was 3.8% (3/79).
The prevalence of individual renal cases in the current study appears to be high. Nephrotic syndrome was the most common with the majority having favorable outcome. There is need to encourage early presentation as the outcome of some of these renal diseases is encouraging, especially when diagnosis and effective management are possible.
肾脏疾病是全球儿童发病和死亡的重要原因,在撒哈拉以南非洲资源匮乏的国家尤为如此。由于患儿就诊晚或未就诊,我们地区关于这些疾病的充分数据有限。
本研究旨在回顾阿巴卡利基联邦教学医院(FETH)3年内儿科肾脏疾病住院患者的模式及治疗结果。
这是一项对埃邦伊州阿巴卡利基FETH医院2011年至2013年期间所有儿童肾脏疾病住院病例的回顾性观察研究。从医院记录中提取的相关临床数据包括患者的生物数据、主要症状、检查结果、实验室检查结果以及使用半结构化问卷记录的治疗和治疗结果。收集的数据使用SPSS软件包16.0版进行分析。使用卡方统计检验比例差异的统计学意义。统计学显著性基于P<0.05。
在研究期间,共收治1780名儿童,其中4.4%(79/1780)患有肾脏疾病。儿童的平均年龄为8.37(5.1)岁。肾病综合征占32.9%(26/79),最为常见,而在个体疾病方面,尿道口狭窄、急性肾损伤和终末期肾病分别占1.3%(1/79),是研究人群中最少见的肾脏疾病。治疗方式与治疗结果之间的关联具有统计学意义(P = 0.03),而其他变量,如年龄(P = 0.42)、性别(P = 0.28)、社会经济状况(P = 0.33)和肾脏疾病类型(P = 1.00)则无统计学意义。病死率为3.8%(3/79)。
本研究中个体肾脏疾病的患病率似乎较高。肾病综合征最为常见,大多数患者预后良好。由于其中一些肾脏疾病的治疗结果令人鼓舞,尤其是在能够进行诊断和有效管理的情况下,因此有必要鼓励患儿尽早就诊。