Haddad Mansour, Ebada Mohamed Elsaed
Department of Clinical Sciences, Faculty of Pharmacy, Philadelphia University, Amman, Jordan.
Department of Pharmacology, National Organization for Drug Control and Research (NODCAR), Agouza, Giza, Egypt.
J Public Health Res. 2017 Apr 13;6(1):818. doi: 10.4081/jphr.2017.818.
Potentially inappropriate drug use, including prescribed and over-the-counter medications, is associated with increased morbidity and mortality. It also contributes to unnecessary expenditure on health services. This survey was undertaken to investigate the incidence of drug misuse and associated socioeconomic/demographic characteristics in Irbid, Jordan.
The present cross section study was conducted using a validated 5-point Likert scale questionnaire to be self-reported by 480 outpatients visiting clinics in three major medical centres in Irbid, Jordan between 20th October 2015 and 27th November 2015. Descriptive analysis, chi-square tests and ordinal logistic regression models were performed.
Patients demonstrated distinctive attitudes towards medication misuse (P<0.001). Whereas around 40% of patients sometimes stopped taking medications earlier than prescribed or doubled the dose in case of missing a dose, three quarters and two fifth of participants neither used expired drugs nor continued to take a drug when adverse drug reactions occurred, respectively. Also, there were significant associations (P<0.05) between patients' attitudes towards misusing medications and characteristics like age, gender, income and marital status. For instance, senior patients (>45 years) tended to double a medication's dose in case of no improvement, and to use others' leftover drugs without medical supervision. Further, male and female patients exhibited different attitude towards misusing medications. Unemployment and little earnings increased the risk for not using drugs properly. Furthermore, married patients were less likely to misuse medications. In particular, the educational level of patients was found to play a major role in modifying patients' attitudes towards potentially inappropriate drug use. Patients holding one or more university degrees were at lower risk for using medications inappropriately.
This survey indicated that northern Jordanians inappropriately used medications to a great extent, suggesting that the current policies should be revised, and emphasising the importance of running public antidrug misuse awareness campaigns and establishing advanced educational/training events targeting healthcare professionals.
潜在的不适当药物使用,包括处方药和非处方药,与发病率和死亡率的增加相关。它还导致了卫生服务方面不必要的支出。本次调查旨在研究约旦伊尔比德药物滥用的发生率以及相关的社会经济/人口特征。
本横断面研究采用经过验证的5级李克特量表问卷,由2015年10月20日至2015年11月27日期间在约旦伊尔比德三个主要医疗中心就诊的480名门诊患者自行报告。进行了描述性分析、卡方检验和有序逻辑回归模型分析。
患者对药物滥用表现出不同的态度(P<0.001)。约40%的患者有时会比规定时间更早停药,或者在漏服一剂时加倍服药剂量,而四分之三的参与者既不使用过期药物,五分之二的参与者在发生药物不良反应时也不会继续服药。此外,患者对药物滥用的态度与年龄、性别、收入和婚姻状况等特征之间存在显著关联(P<0.05)。例如,老年患者(>45岁)在病情无改善时倾向于加倍服药剂量,并且在没有医疗监督的情况下使用他人剩余的药物。此外,男性和女性患者对药物滥用表现出不同的态度。失业和低收入增加了不适当用药的风险。此外,已婚患者滥用药物的可能性较小。特别是,发现患者的教育水平在改变患者对潜在不适当药物使用的态度方面起着主要作用。拥有一个或多个大学学位的患者不适当用药的风险较低。
本次调查表明,约旦北部居民在很大程度上存在不适当用药的情况,这表明当前政策应予以修订,并强调开展公众预防药物滥用意识宣传活动以及针对医疗保健专业人员开展高级教育/培训活动的重要性。