运用关节镜观察柔肝药物对膝关节骨关节炎的疗效。
USING ARTHROSCOPY TO OBSERVE THE EFFECT OF LIVER-SOFTENING MEDICINE ON KNEE OSTEOARTHRITIS.
作者信息
Dai Chong-Hua, Sun Jun, Gu Xin-Feng, Zheng Yu-Xin
机构信息
Luliang County People's Hospital, Qujing City, Yunnan Province 655600, China.
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China.
出版信息
Afr J Tradit Complement Altern Med. 2017 Mar 1;14(3):12-21. doi: 10.21010/ajtcam.v14i3.2. eCollection 2017.
BACKGROUND
Arthroscopy was used to observe the clinical effect of liver-softening medicine for treating knee osteoarthritis (OA).
MATERIALS AND METHODS
Forty knee OA patients with cartilage classifications of Outerbridge grade II, III, or II plus III determined via arthroscopy were randomly assigned to a treatment of liver-softening medicine plus glucosamine or a control treatment of glucosamine alone. Clinical observation and determination of the comprehensive effect score were performed at 60, 120, and 180 days. A second arthroscopy was performed at 180 days.
RESULTS
Signs and symptoms significantly improved at different time points in the treatment group. The effects in the treatment group were better than those in the control group. When analyzing the cartilage during the second arthroscopy, no further degeneration was observed.
CONCLUSIONS
After arthroscopic debridement, the treatment of knee OA with liver-softening medicine in conjunction with glucosamine is a feasible and effective solution.
背景
采用关节镜观察软坚药物治疗膝关节骨关节炎（OA）的临床效果。
材料与方法
通过关节镜确定软骨外布里奇分级为II级、III级或II级加III级的40例膝关节OA患者被随机分配接受软坚药物加氨基葡萄糖治疗或单独接受氨基葡萄糖对照治疗。在60天、120天和180天时进行临床观察并确定综合疗效评分。在180天时进行第二次关节镜检查。
结果
治疗组在不同时间点的体征和症状有显著改善。治疗组的效果优于对照组。在第二次关节镜检查时分析软骨，未观察到进一步退变。
结论
关节镜清创术后，软坚药物联合氨基葡萄糖治疗膝关节OA是一种可行且有效的解决方案。
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