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本文引用的文献

1
Use of clinical prediction rules and D-dimer tests in the diagnostic management of pregnant patients with suspected acute pulmonary embolism.临床预测规则和D - 二聚体检测在疑似急性肺栓塞孕妇诊断管理中的应用
Blood Rev. 2017 Mar;31(2):31-36. doi: 10.1016/j.blre.2016.09.003. Epub 2016 Sep 29.
2
Yield of CT Pulmonary Angiography in the Emergency Department When Providers Override Evidence-based Clinical Decision Support.当医疗人员推翻基于证据的临床决策支持时,急诊科CT肺动脉造影的诊断率
Radiology. 2017 Mar;282(3):717-725. doi: 10.1148/radiol.2016151985. Epub 2016 Sep 30.
3
Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion.将放射影像学置于线性无阈假说之下:一个具有相当比例的不合逻辑的推理。
J Nucl Med. 2017 Jan;58(1):1-6. doi: 10.2967/jnumed.116.180182. Epub 2016 Aug 4.
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Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians.疑似急性肺栓塞患者评估:美国医师学院临床指南委员会的最佳实践建议。
Ann Intern Med. 2015 Nov 3;163(9):701-11. doi: 10.7326/M14-1772. Epub 2015 Sep 29.
5
Chasing Pulmonary Emboli: Let's Agree on One Big Thing.追踪肺栓塞:让我们在一件大事上达成共识。
Am J Med. 2013 Jan;126(1):3. doi: 10.1016/j.amjmed.2012.07.013. Epub 2012 Nov 20.
6
Adherence to PIOPED II investigators' recommendations for computed tomography pulmonary angiography.对 PIOPED II 研究者推荐的计算机断层肺动脉造影的依从性。
Am J Med. 2013 Jan;126(1):36-42. doi: 10.1016/j.amjmed.2012.05.028. Epub 2012 Nov 20.
7
SNM practice guideline for lung scintigraphy 4.0.核医学学会肺闪烁扫描实践指南4.0
J Nucl Med Technol. 2012 Mar;40(1):57-65. doi: 10.2967/jnmt.111.101386. Epub 2012 Jan 26.
8
An official American Thoracic Society/Society of Thoracic Radiology clinical practice guideline: evaluation of suspected pulmonary embolism in pregnancy.美国胸科学会/胸放射学会官方临床实践指南:妊娠疑似肺栓塞的评估。
Am J Respir Crit Care Med. 2011 Nov 15;184(10):1200-8. doi: 10.1164/rccm.201108-1575ST.
9
Critical issues in the evaluation and management of adult patients presenting to the emergency department with suspected pulmonary embolism.成人患者因疑似肺栓塞而到急诊科就诊的评估和管理中的关键问题。
Ann Emerg Med. 2011 Jun;57(6):628-652.e75. doi: 10.1016/j.annemergmed.2011.01.020.
10
Prospective evaluation of real-time use of the pulmonary embolism rule-out criteria in an academic emergency department.前瞻性评估肺栓塞排除标准在学术急诊中的实时应用。
Acad Emerg Med. 2010 Sep;17(9):1016-9. doi: 10.1111/j.1553-2712.2010.00826.x.

年轻女性的CT肺动脉造影

CT Pulmonary Angiography in Young Women.

作者信息

Stein Paul D, Matta Fadi, Hughes Kate E, Hughes Mary J

机构信息

1 Department of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.

出版信息

Clin Appl Thromb Hemost. 2018 Apr;24(3):423-428. doi: 10.1177/1076029617707038. Epub 2017 May 8.

DOI:10.1177/1076029617707038
PMID:28480751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6714652/
Abstract

The purpose was to determine whether young women in the emergency department who received computed tomographic (CT) pulmonary angiograms were evaluated to receive lower dose imaging or no imaging, recognizing that the risks of radiation are particularly high in young women. This was a retrospective cohort investigation of women aged 18 to 29 years seen for suspected acute pulmonary embolism in emergency departments of 5 regional hospitals from May 1, 2015 to April 30, 2016. Computed tomographic (CT) pulmonary angiograms were obtained in 379 young women. Pulmonary embolism was diagnosed by CT angiography in 2.1%. A Wells probability score could be calculated in 11.9%. D-dimer was obtained in 46.2% and a chest radiograph was obtained in 41.7%. Among patients with a normal chest radiograph, 3.9% had a lung scan. Venous ultrasound of the lower extremities was obtained in 1.8%. Each had an elevated D-dimer. Among the young women who received CT angiograms, 53 were pregnant. In 17.0% of pregnant women, a Wells clinical probability score could be calculated from the medical record. D-dimer in pregnant women was obtained in 30.2%, chest radiograph in 22.6%, lung scan in 11.3%, and venous ultrasound of the lower extremities in none. In conclusion, young women and pregnant women often received CT pulmonary angiograms for suspected acute pulmonary embolism without an objective clinical assessment, measurement of D-dimer, lung scintiscan, or venous ultrasound, which may have eliminated the need for CT pulmonary angiography in many instances.

摘要

目的是确定急诊科中接受计算机断层扫描(CT)肺血管造影的年轻女性是否接受了低剂量成像评估或未接受成像评估,因为认识到年轻女性的辐射风险特别高。这是一项回顾性队列研究,研究对象为2015年5月1日至2016年4月30日期间在5家地区医院急诊科就诊的疑似急性肺栓塞的18至29岁女性。379名年轻女性接受了计算机断层扫描(CT)肺血管造影。CT血管造影诊断肺栓塞的比例为2.1%。11.9%的患者可计算Wells概率评分。46.2%的患者检测了D-二聚体,41.7%的患者进行了胸部X光检查。胸部X光检查正常的患者中,3.9%进行了肺部扫描。1.8%的患者进行了下肢静脉超声检查,这些患者的D-二聚体均升高。在接受CT血管造影的年轻女性中,53名怀孕。17.0%的孕妇可根据病历计算Wells临床概率评分。30.2%的孕妇检测了D-二聚体,22.6%的孕妇进行了胸部X光检查,11.3%的孕妇进行了肺部扫描,无一例进行下肢静脉超声检查。总之,年轻女性和孕妇在疑似急性肺栓塞时经常接受CT肺血管造影,而没有进行客观的临床评估、D-二聚体测量、肺闪烁扫描或静脉超声检查,而在许多情况下这些检查可能会消除对CT肺血管造影的需求。