Stein Paul D, Matta Fadi, Hughes Kate E, Hughes Mary J
1 Department of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.
Clin Appl Thromb Hemost. 2018 Apr;24(3):423-428. doi: 10.1177/1076029617707038. Epub 2017 May 8.
The purpose was to determine whether young women in the emergency department who received computed tomographic (CT) pulmonary angiograms were evaluated to receive lower dose imaging or no imaging, recognizing that the risks of radiation are particularly high in young women. This was a retrospective cohort investigation of women aged 18 to 29 years seen for suspected acute pulmonary embolism in emergency departments of 5 regional hospitals from May 1, 2015 to April 30, 2016. Computed tomographic (CT) pulmonary angiograms were obtained in 379 young women. Pulmonary embolism was diagnosed by CT angiography in 2.1%. A Wells probability score could be calculated in 11.9%. D-dimer was obtained in 46.2% and a chest radiograph was obtained in 41.7%. Among patients with a normal chest radiograph, 3.9% had a lung scan. Venous ultrasound of the lower extremities was obtained in 1.8%. Each had an elevated D-dimer. Among the young women who received CT angiograms, 53 were pregnant. In 17.0% of pregnant women, a Wells clinical probability score could be calculated from the medical record. D-dimer in pregnant women was obtained in 30.2%, chest radiograph in 22.6%, lung scan in 11.3%, and venous ultrasound of the lower extremities in none. In conclusion, young women and pregnant women often received CT pulmonary angiograms for suspected acute pulmonary embolism without an objective clinical assessment, measurement of D-dimer, lung scintiscan, or venous ultrasound, which may have eliminated the need for CT pulmonary angiography in many instances.
目的是确定急诊科中接受计算机断层扫描(CT)肺血管造影的年轻女性是否接受了低剂量成像评估或未接受成像评估,因为认识到年轻女性的辐射风险特别高。这是一项回顾性队列研究,研究对象为2015年5月1日至2016年4月30日期间在5家地区医院急诊科就诊的疑似急性肺栓塞的18至29岁女性。379名年轻女性接受了计算机断层扫描(CT)肺血管造影。CT血管造影诊断肺栓塞的比例为2.1%。11.9%的患者可计算Wells概率评分。46.2%的患者检测了D-二聚体,41.7%的患者进行了胸部X光检查。胸部X光检查正常的患者中,3.9%进行了肺部扫描。1.8%的患者进行了下肢静脉超声检查,这些患者的D-二聚体均升高。在接受CT血管造影的年轻女性中,53名怀孕。17.0%的孕妇可根据病历计算Wells临床概率评分。30.2%的孕妇检测了D-二聚体,22.6%的孕妇进行了胸部X光检查,11.3%的孕妇进行了肺部扫描,无一例进行下肢静脉超声检查。总之,年轻女性和孕妇在疑似急性肺栓塞时经常接受CT肺血管造影,而没有进行客观的临床评估、D-二聚体测量、肺闪烁扫描或静脉超声检查,而在许多情况下这些检查可能会消除对CT肺血管造影的需求。