水平基因转移不是人类基因组的标志。
Horizontal gene transfer is not a hallmark of the human genome.
机构信息
Departments of Biomedical Engineering, Computer Science and Biostatistics, Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA.
出版信息
Genome Biol. 2017 May 8;18(1):85. doi: 10.1186/s13059-017-1214-2.
Abstract
Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as having the highest certainty of having been horizontally transferred, as well as 17 further genes from the 2001 human genome article, and find little or no evidence to support claims of horizontal gene transfer (HGT).Please see related Research article: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3.
摘要
克利斯普等人最近报告称，有 145 个人类基因从远缘物种中水平转移而来。在这里，我重新分析了克利斯普等人列为具有最高水平转移确定性的那些基因，以及 2001 年人类基因组文章中的另外 17 个基因，几乎没有或没有证据支持水平基因转移（HGT）的说法。请参阅相关研究文章：https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0607-3。
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