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[孕期烧心与反流。胃仙-U混悬液治疗的疗效与安全性]

[Heartburn and regurgitation in pregnancy. Efficacy and innocuousness of treatment with Gaviscon suspension].

作者信息

Uzan M, Uzan S, Sureau C, Richard-Berthe C

机构信息

Maternité Baudelocque, Hôpital Cochin, Paris.

出版信息

Rev Fr Gynecol Obstet. 1988 Jul-Sep;83(7-9):569-72.

PMID:2848305
Abstract

This open trial was conducted in 50 pregnant women, presenting during the 2nd and 3rd trimesters of their pregnancy typical symptoms of gastro-esophageal reflux (pyrosis, regurgitations, retro-sternal burning sensations, dyspepsia, epigastric burning). The treatment with Gaviscon, suspension to drink, lasted 1 month at a dose of 2 tablespoons, 4 times/day after meals and in the evening at bedtime. After one month, all symptoms were improved, in a statistically significant fashion, regarding their frequency, intensity and duration. The efficacy is considered positive in 98 p. cent of the cases; the patient's impression is favorable in 70 p. cent of the cases. Tolerance is excellent and the medication is satisfactorily accepted.

摘要

这项开放性试验在50名孕妇中进行,她们在妊娠中期和晚期出现典型的胃食管反流症状(烧心、反流、胸骨后烧灼感、消化不良、上腹部烧灼感)。使用胃仙-U混悬液治疗,持续1个月,剂量为2汤匙,每日4次,饭后及晚上睡前服用。1个月后,所有症状在频率、强度和持续时间方面均有显著改善。98%的病例疗效被认为是阳性的;70%的病例患者感觉良好。耐受性极佳,药物接受度令人满意。

相似文献

1
[Heartburn and regurgitation in pregnancy. Efficacy and innocuousness of treatment with Gaviscon suspension].[孕期烧心与反流。胃仙-U混悬液治疗的疗效与安全性]
Rev Fr Gynecol Obstet. 1988 Jul-Sep;83(7-9):569-72.
2
[Treatment of gastro-esophageal reflux using a potable gaviscon suspension].[使用可饮用的胃仙-U混悬液治疗胃食管反流]
Med Chir Dig. 1982;11(4):289-95.
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Comparative study of Algicon versus Gaviscon in symptomatic gastro-oesophageal reflux.症状性胃食管反流中Algicon与Gaviscon的对比研究
Br J Clin Pract Suppl. 1989 Feb;66:52-5; discussion 61-4.
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An open-label, multicentre study to assess the safety and efficacy of a novel reflux suppressant (Gaviscon Advance) in the treatment of heartburn during pregnancy.一项开放标签、多中心研究,旨在评估一种新型抗反流药物(加味善胃得加强版)治疗孕期烧心的安全性和有效性。
Int J Clin Pract. 2003 Apr;57(3):175-9.
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Comparative study of Algicon suspension and magnesium trisilicate mixture in the treatment of reflux dyspepsia of pregnancy.阿尔吉康混悬液与三硅酸镁合剂治疗妊娠反流性消化不良的对比研究
Br J Clin Pract Suppl. 1989 Feb;66:48-51; discussion 61-4.
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Algicon in the management of gastro-oesophageal reflux.阿尔吉康在胃食管反流管理中的应用
Br J Clin Pract Suppl. 1989 Feb;66:56-8; discussion 61-4.
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[Gastroesophageal reflux. Results of a multicenter study of 170 patients on the therapeutic value of the Gaviscon drinkable suspension].[胃食管反流。170例患者关于加胃斯康可饮用混悬液治疗价值的多中心研究结果]
Med Chir Dig. 1980;9(6):535-9.
8
[Gaviscon in reflux symptoms. Results of a drug monitoring study].[胃复安治疗反流症状。一项药物监测研究的结果]
Fortschr Med. 1990 Oct 30;108(31):598-600.
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[Evaluation of action, efficacy, and onset dynamics of a single dose of alginates in patients with heartburn and GERD].[单剂量藻酸盐对烧心和胃食管反流病患者的作用、疗效及起效动力学评估]
Eksp Klin Gastroenterol. 2009(4):77-85.
10
A comparative crossover study on the treatment of heartburn and epigastric pain: Liquid Gaviscon and a magnesium--aluminium antacid gel.一项关于胃灼热和上腹部疼痛治疗的比较性交叉研究:液状胃仙-U与镁铝抗酸凝胶。
J Int Med Res. 1980;8(4):300-2. doi: 10.1177/030006058000800411.

引用本文的文献

1
Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy.一种成筏型海藻酸盐反流抑制剂(液状胃仙-U)治疗妊娠期烧心的安全性和有效性评估
ISRN Obstet Gynecol. 2012;2012:481870. doi: 10.5402/2012/481870. Epub 2012 Nov 4.