Kojima S, Matsuyama K, Ishii E
Division of Hematology/Oncology, Children's Medical Center, Nagoya, Japan.
Acta Haematol. 1988;80(3):171-2. doi: 10.1159/000205626.
Recent study has shown that the human parvovirus (HPV) is a causative agent of aplastic crisis in hemolytic anemias. In subjects without shortened red blood cell life span, HPV is not associated with symptomatic anemia. A case of iron deficiency anemia revealed by HPV linked to erythroblastopenia is described in a child. On admission, the serum iron was not decreased and other blood chemistry tests were also not consistent with the diagnosis of iron deficiency anemia. Abrupt cessation of erythropoiesis induced by HPV infection appeared to prolong plasma iron clearance, which elevated serum iron concentration.
最近的研究表明，人类细小病毒（HPV）是溶血性贫血再生障碍危象的病原体。在红细胞寿命未缩短的个体中，HPV与症状性贫血无关。本文描述了一名儿童因HPV相关的成红细胞减少症导致缺铁性贫血的病例。入院时，血清铁未降低，其他血液化学检查结果也与缺铁性贫血的诊断不符。HPV感染引起的红细胞生成突然停止似乎延长了血浆铁清除时间，从而提高了血清铁浓度。
