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[嗜麦芽窄食单胞菌引起的快速进展性出血性肺炎,发生在骨髓增生异常综合征患者骨髓移植后早期]

[Rapidly progressive hemorrhagic pneumonia caused by Stenotrophomonas maltophilia occurring early after bone marrow transplantation in a patient with myelodysplastic syndrome].

作者信息

Katayama Oju, Kitagawa Tomoya, Onaka Takashi, Yonezawa Akihito

机构信息

Department of Hematology, Kokura Memorial Hospital.

出版信息

Rinsho Ketsueki. 2017;58(4):323-325. doi: 10.11406/rinketsu.58.323.

Abstract

A 44-year-old woman had repeated bacterial infections because of hypoplastic myelodysplastic syndrome; therefore, she underwent allogeneic hematopoietic cell transplantation. Broad spectrum antibiotics were administered because she had bacterial infection and pneumonia 2 weeks before undergoing transplantation. On day19 after transplantation, she suddenly presented with hemoptysis. Stenotrophomonas maltophilia was considered to be the cause of hemorrhagic pneumonia, which required ventilation support, massive transfusion, and catecholamine administration. However, she died 8 h after the onset of hemoptysis. Severe S. maltophilia infections may occur in patients with immunocompromised conditions such as those after allogeneic hematopoietic cell transplantation.

摘要

一名44岁女性因骨髓发育不良综合征发育不全而反复发生细菌感染,因此接受了异基因造血细胞移植。由于她在移植前2周出现细菌感染和肺炎,所以给予了广谱抗生素治疗。移植后第19天,她突然出现咯血。嗜麦芽窄食单胞菌被认为是出血性肺炎的病因,这需要通气支持、大量输血和给予儿茶酚胺。然而,她在咯血发作后8小时死亡。严重的嗜麦芽窄食单胞菌感染可能发生在免疫功能低下的患者中,如异基因造血细胞移植后的患者。

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