Li Rong, Leng Ai-Min, Liu Ting, Zhou Yan-Wu, Zeng Jun-Xian, Liu Xiao-Ming, Hu Ting-Zi, Jiang Xiao-Xia, Zhang Lin-Fang, Xu Can-Xia
Department of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, China.
Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Changsha, Hunan 410013, China.
Biomed Res Int. 2017;2017:5090534. doi: 10.1155/2017/5090534. Epub 2017 Apr 18.
Many factors have been reported to affect the long-term survival of gastric carcinoma patients after gastrectomy; the present study took the first attempt to find out the potential role of weekday carried out surgery in the postoperative prognosis of gastric cancer patients. 463 gastric cancer patients have been followed up successfully. Pearson test was used for univariate analyses. Survival curves were constructed by using Kaplan-Meier method and evaluated by using the log-rank test. The Cox proportional hazard regression model was used to find out the risk factors, and subgroup analysis was conducted to rule out confounding factors. We found that the patients who underwent gastrectomy on the later weekday (Wednesday-Friday) more easily suffered from a higher postoperative morbidity. Weekday of surgery was one of the independent indicators for the prognosis of patients after gastric cancer surgery. However, the role of weekday of surgery was significantly weakened in the complications group. In conclusion, surgery performed in the later weekday was more likely to lead to increased postoperative complications and an unfavorable role in prognosis of Chinese gastric cancer patients after curative gastrectomy.
据报道,许多因素会影响胃癌患者胃切除术后的长期生存;本研究首次尝试探究手术进行的工作日对胃癌患者术后预后的潜在作用。463例胃癌患者得到成功随访。采用Pearson检验进行单因素分析。使用Kaplan-Meier方法构建生存曲线,并通过对数秩检验进行评估。采用Cox比例风险回归模型找出危险因素,并进行亚组分析以排除混杂因素。我们发现,在工作日较晚时间(周三至周五)接受胃切除术的患者更容易出现较高的术后发病率。手术的工作日是胃癌手术后患者预后的独立指标之一。然而,手术工作日在并发症组中的作用明显减弱。总之,在工作日较晚时间进行手术更有可能导致术后并发症增加,对中国胃癌患者根治性胃切除术后的预后产生不利影响。