Fan Lizhi, He Ying, Li Yufeng, Li Xinxin, Liu Dan, Wang Rui
Cadre Ward (Geriatric), The First Hospital of Harbin, Harbin, Heilongjiang 150000, P.R. China.
Department of Ultrasonography, Hongqi Hospital Affiliated to Mudanjiang Medical College, Mudanjiang, Heilongjiang 157000, P.R. China.
Oncol Lett. 2023 Oct 31;26(6):537. doi: 10.3892/ol.2023.14124. eCollection 2023 Dec.
Gastrectomy is a technically demanding procedure for gastric cancer patients that is associated with different degrees of postoperative complications (POCs). Perioperative traditional Chinese medicine (TCM) nursing intervention presents benefits for improving the survival of patients with gastric cancer. However, the effects of TCM nursing intervention on POCs and the prognosis of patients with gastric cancer following surgery are far from clear. In the present study, the effects of TCM nursing intervention on POCs, postoperative physical capacity, metal status, long-term survival and recurrence were investigated in patients with gastric cancer after gastrectomy. In total, 1,032 patients with gastric cancer were included in the study. The patients underwent a gastrectomy and were randomly divided into two groups: The TCM nursing intervention group (TCM group; n=520) and the routine nursing intervention group (control group; n=512). Postoperative pain score, hospital stay, POCs, postoperative gastrointestinal function, frequency of postoperative symptoms, inflammatory index, quality of life, physical capacity, mental status, survival and recurrence were compared after gastrectomy in the TCM and control groups. The treatment-related adverse events of TCM in patients after gastrectomy were recorded in the TCM nursing intervention group. The outcomes showed that TCM nursing intervention decreased the postoperative pain score and hospital stay, improved gastrointestinal function, and decreased the POCs and the inflammation index compared with the control group. In addition, TCM nursing intervention improved physical capacity, quality of life, depression, anxiety, immune activity, long-term survival and recurrence in patients with gastric cancer after gastrectomy. Furthermore, TCM nursing intervention was only associated with a low number of adverse events. In conclusion, outcomes in this study indicate that perioperative TCM nursing intervention improves POCs, mental status, long-term survival and reduces the recurrence of patients with gastric cancer, suggesting that TCM nursing intervention is efficacious and safe with regard to improving the prognosis in these patients after gastrectomy (Retrospective clinical trial registration number, 2015001CW1; name of the register, The First Hospital of Harbin; date of registration, May 7, 2015).
胃切除术对于胃癌患者来说是一项技术要求很高的手术,且与不同程度的术后并发症(POC)相关。围手术期中医护理干预对提高胃癌患者的生存率有益。然而,中医护理干预对胃癌患者术后POC及预后的影响尚不清楚。在本研究中,对胃癌患者胃切除术后中医护理干预对POC、术后身体能力、金属状态、长期生存及复发的影响进行了调查。本研究共纳入1032例胃癌患者。这些患者接受了胃切除术,并随机分为两组:中医护理干预组(中医组;n = 520)和常规护理干预组(对照组;n = 512)。比较了中医组和对照组胃切除术后的术后疼痛评分、住院时间、POC、术后胃肠功能、术后症状发生频率、炎症指标、生活质量、身体能力、精神状态、生存及复发情况。在中医护理干预组记录了胃切除术后患者中医治疗相关的不良事件。结果显示,与对照组相比,中医护理干预降低了术后疼痛评分和住院时间,改善了胃肠功能,降低了POC和炎症指标。此外,中医护理干预改善了胃切除术后胃癌患者的身体能力、生活质量、抑郁、焦虑、免疫活性、长期生存及复发情况。此外,中医护理干预仅与少量不良事件相关。总之,本研究结果表明围手术期中医护理干预改善了胃癌患者的POC、精神状态、长期生存并降低了复发率,提示中医护理干预在改善这些患者胃切除术后的预后方面有效且安全(回顾性临床试验注册号,2015001CW1;注册机构名称,哈尔滨医科大学附属第一医院;注册日期,2015年5月7日)