口蹄疫病毒（FMDV）重组体中的交叉区域对应于局部二级结构较高的区域。
Crossover regions in foot-and-mouth disease virus (FMDV) recombinants correspond to regions of high local secondary structure.
作者信息
Wilson V, Taylor P, Desselberger U
机构信息
Institute of Virology, University of Glasgow, Scotland.
出版信息
Arch Virol. 1988;102(1-2):131-9. doi: 10.1007/BF01315570.
Abstract
The RNA genome of foot-and-mouth disease virus (FMDV) was analysed for the degree of inverted complementarity and thus potential secondary structure using the procedure of Pustell and Kafatos [Nucleic Acids Res (1982) 10: 4765-4782]. Regions of crossover in 42 FMDV recombinants [King et al. (1985) Virus Res 3: 373-384; Saunders et al. (1985) J Virol 56: 921-929] and regions lacking crossovers were assigned an average secondary structure score against which the number of observed recombinants was plotted. In general it was found that the mean value of potential secondary structure is significantly higher in crossover zones than in recombination-free zones. Recombination increased much more steeply with increasing secondary structure in the part of the genome coding for non-structural proteins than in the 5' third of the genome coding for structural proteins.
摘要
采用普斯泰尔和卡法托斯的方法[《核酸研究》（1982年）10: 4765 - 4782]，分析口蹄疫病毒（FMDV）的RNA基因组的反向互补程度以及潜在的二级结构。对42个FMDV重组体中的交叉区域[金等人（1985年）《病毒研究》3: 373 - 384；桑德斯等人（1985年）《病毒学杂志》56: 921 - 929]和无交叉区域赋予平均二级结构得分，并据此绘制观察到的重组体数量。总体而言，发现交叉区域潜在二级结构的平均值显著高于无重组区域。与编码结构蛋白的基因组5'端三分之一区域相比，在编码非结构蛋白的基因组部分，随着二级结构增加，重组增加得更为陡峭。
相似文献
1
Crossover regions in foot-and-mouth disease virus (FMDV) recombinants correspond to regions of high local secondary structure.
Arch Virol. 1988;102(1-2):131-9. doi: 10.1007/BF01315570.
2
Potential secondary and tertiary structure in the genomic RNA of foot and mouth disease virus.
Nucleic Acids Res. 1987 Sep 11;15(17):7067-79. doi: 10.1093/nar/15.17.7067.
3
Recombination in RNA.
Cell. 1982 Jul;29(3):921-8. doi: 10.1016/0092-8674(82)90454-8.
4
Multiple sites of recombination within the RNA genome of foot-and-mouth disease virus.
Virus Res. 1985 Nov;3(4):373-84. doi: 10.1016/0168-1702(85)90437-x.
5
Identification and characterization of foot-and-mouth disease virus O1 Burgwedel/1987 as an intertypic recombinant.
J Gen Virol. 1992 Mar;73 ( Pt 3):613-9. doi: 10.1099/0022-1317-73-3-613.
6
A single nucleotide substitution in the internal ribosome entry site of foot-and-mouth disease virus leads to enhanced cap-independent translation in vivo.
J Virol. 1993 Jul;67(7):3748-55. doi: 10.1128/JVI.67.7.3748-3755.1993.
7
Detection of foot-and-mouth disease virus RNA in clinical samples and cell culture isolates by amplification of the capsid coding region.
J Virol Methods. 1993 Apr;42(1):53-61. doi: 10.1016/0166-0934(93)90176-r.
8
Isolation and biochemical characterization of intertypic recombinants of foot-and-mouth disease virus.
Virus Res. 1985 Jul;3(1):87-100. doi: 10.1016/0168-1702(85)90044-9.
9
Sequence variation in the gene for the immunogenic capsid protein VP1 of foot-and-mouth disease virus type A.
Proc Natl Acad Sci U S A. 1985 May;82(9):2618-22. doi: 10.1073/pnas.82.9.2618.
10
Sequence of the S fragment of foot-and-mouth disease virus type A12.
Virus Genes. 1994 Mar;8(2):173-5. doi: 10.1007/BF01703076.
引用本文的文献
1
Evaluation of Potential In Vitro Recombination Events in Codon Deoptimized FMDV Strains.
Viruses. 2023 Mar 2;15(3):670. doi: 10.3390/v15030670.
2
Foot-and-Mouth Disease Virus Interserotypic Recombination in Superinfected Carrier Cattle.
Pathogens. 2022 Jun 3;11(6):644. doi: 10.3390/pathogens11060644.
3
Characterization of a triple-recombinant, reassortant rotavirus strain from the Dominican Republic.
J Gen Virol. 2017 Feb;98(2):134-142. doi: 10.1099/jgv.0.000688. Epub 2017 Feb 24.
4
Genetic variability of human respiratory syncytial virus A strains circulating in Ontario: a novel genotype with a 72 nucleotide G gene duplication.
PLoS One. 2012;7(3):e32807. doi: 10.1371/journal.pone.0032807. Epub 2012 Mar 28.
5
Phylogenetic analyses of the polyprotein coding sequences of serotype O foot-and-mouth disease viruses in East Africa: evidence for interserotypic recombination.
Virol J. 2010 Aug 23;7:199. doi: 10.1186/1743-422X-7-199.
6
Analysis of synonymous codon usage in foot-and-mouth disease virus.
Vet Res Commun. 2010 Apr;34(4):393-404. doi: 10.1007/s11259-010-9359-4. Epub 2010 Apr 28.
7
Genetic analysis of foot-and-mouth disease virus serotype A of Indian origin and detection of positive selection and recombination in leader protease-and capsid-coding regions.
J Biosci. 2009 Mar;34(1):85-101. doi: 10.1007/s12038-009-0011-9.
8
Thermal inactivation of foot-and-mouth disease viruses in suspension.
Appl Environ Microbiol. 2007 Nov;73(22):7177-84. doi: 10.1128/AEM.00629-07. Epub 2007 Jul 27.
9
Foot-and-mouth disease.
Clin Microbiol Rev. 2004 Apr;17(2):465-93. doi: 10.1128/CMR.17.2.465-493.2004.
10
A human rotavirus with rearranged genes 7 and 11 encodes a modified NSP3 protein and suggests an additional mechanism for gene rearrangement.
J Virol. 2001 Aug;75(16):7305-14. doi: 10.1128/JVI.75.16.7305-7314.2001.
本文引用的文献
1
The genetics of foot and mouth disease virus.
Rev Sci Tech. 1986 Jun;5(2):279-297. doi: 10.20506/rst.5.2.236.
2
EVIDENCE OF GENETIC RECOMBINATION IN FOOT-AND-MOUTH DISEASE VIRUS.
Virology. 1965 Jan;25:48-54. doi: 10.1016/0042-6822(65)90250-3.
3
Genetic recombination with Newcastle disease virus, polioviruses, and influenza.
Cold Spring Harb Symp Quant Biol. 1962;27:303-9. doi: 10.1101/sqb.1962.027.001.028.
4
Genetic recombination with poliovirus type 1. Studies of crosses between a normal horse serum-resistant mutant and several guanidine-resistant mutants of the same strain.
Virology. 1963 May;20:107-19. doi: 10.1016/0042-6822(63)90145-4.
5
La Crosse virions contain a primer-stimulated RNA polymerase and a methylated cap-dependent endonuclease.
J Virol. 1984 Oct;52(1):215-22. doi: 10.1128/JVI.52.1.215-222.1984.
6
Intertypic recombination in poliovirus: genetic and biochemical studies.
Virology. 1983 Jan 15;124(1):121-32. doi: 10.1016/0042-6822(83)90295-7.
7
Recombination in RNA.
Cell. 1982 Jul;29(3):921-8. doi: 10.1016/0092-8674(82)90454-8.
8
A high speed, high capacity homology matrix: zooming through SV40 and polyoma.
Nucleic Acids Res. 1982 Aug 11;10(15):4765-82. doi: 10.1093/nar/10.15.4765.
9
A sensitive method for the detection and isolation of recombinants of foot-and-mouth disease virus.
J Gen Virol. 1981 Apr;53(Pt 2):333-42. doi: 10.1099/0022-1317-53-2-333.
10
Biochemical evidence for intertypic genetic recombination of polioviruses.
FEBS Lett. 1980 Aug 25;118(1):109-12. doi: 10.1016/0014-5793(80)81229-4.
Zotero 插件