Reithmann Christopher
Medizinische Klinik 1, HELIOS Klinikum München West, Akademisches Lehrkrankenhaus der Ludwig-Maximilians-Universität München, Steinerweg 5, 81241, München, Deutschland.
Herzschrittmacherther Elektrophysiol. 2017 Jun;28(2):193-198. doi: 10.1007/s00399-017-0502-6. Epub 2017 May 8.
Macroreentry in the His-Purkinje system can result in sustained ventricular tachycardia (VT) termed bundle branch reentry VT. Bundle branch reentry is usually associated with His-Purkinje disease and depressed left ventricular function. In the case of typical bundle branch reentry, the right bundle is activated in the anterograde direction and ventricular depolarization begins at the distal end of the right bundle on the ventricular septum generating a typical left bundle branch block QRS morphology. However, atypical surface ECGs can also be found in patients with severe left ventricular dysfunction and involvement of the right ventricle complicating the diagnosis of bundle branch reentry VT. It is important to diagnose bundle branch reentry VT because patients with bundle branch reentry VT may suffer from a high rate of serial implantable cardioverter defibrillator (ICD) interventions based on VT recurrences due to immediate reinitiation of the arrhythmia. Ablation of the right bundle branch easily cures bundle branch reentry VT and can prevent frequent ICD interventions. After ablation of bundle branch reentry VT, mortality remains high due to the severe left ventricular dysfunction in many patients, and the patients are candidates for cardiac resynchronization therapy (CRT-D).
希氏-浦肯野系统中的大折返可导致持续性室性心动过速(VT),称为束支折返性室速。束支折返通常与希氏-浦肯野疾病及左心室功能减退有关。在典型束支折返的情况下,右束支沿顺行方向被激活,心室去极化始于室间隔上右束支的远端,产生典型的左束支阻滞QRS形态。然而,在严重左心室功能障碍且右心室受累的患者中也可发现不典型的体表心电图,这使得束支折返性室速的诊断变得复杂。诊断束支折返性室速很重要,因为束支折返性室速患者可能因心律失常立即复发导致室速复发,从而接受高比例的连续植入式心脏复律除颤器(ICD)干预。消融右束支可轻易治愈束支折返性室速,并可预防频繁的ICD干预。在消融束支折返性室速后,由于许多患者存在严重的左心室功能障碍,死亡率仍然很高,这些患者是心脏再同步治疗(CRT-D)的候选者。