Laboratory of Applied Animal Biology, University Badji Mokhtar of Annaba, 23000, Annaba, Algeria.
INSERM UMR 1231 Equipe - Lipoproteins and lipid transfers in sterile and septic inflammation (LIPNESS), Université Bourgogne Franche Comté (UBFC), UFR SVTE, 6 Boulevard Gabriel, 21000, Dijon, France.
Environ Sci Pollut Res Int. 2018 Jul;25(19):18242-18250. doi: 10.1007/s11356-017-9031-4. Epub 2017 May 8.
Donax trunculus is the most consumed bivalve by the local population of the Northeast Algeria for its nutritional value. Therefore, the aim of the current study was to determine the effects of cadmium (Cd), a known toxic metal, on the alterations in main essential omega-3 fatty acids, i.e., eicosapentaenoic acid (EPA; C20:5n-3) and docosahexaenoic acid (DHA; C22:6n-3), in male and female gonads of D. trunculus during the reproduction period at spring (before spawning). Additionally, this work seeks to describe the relation between EPA and DHA with non-methylene-interrupted dienoic (NMID) fatty acids, and explores their possible contribution of to protect against Cd stress. The samples were collected at El Battah, a relatively clean sea shore, and reared in the laboratory. Physico-chemical parameters such as temperature, pH, salinity, and dissolved oxygen were measured. Cd was added to the rearing water at two sublethal concentrations (LC and LC-96h, as determined previously). A two-way ANOVA analysis indicated significant effects of concentrations and genders for both fatty acids. Our results showed a significant reduction in EPA and DHA concentrations in the both genders, with a strong effect in females. There was also a negative correlation between NMID fatty acids and the two essential omega-3 fatty acids for each gender.
鼓蚶是阿尔及利亚东北部当地居民消耗最多的双壳贝类，因其具有营养价值。因此，本研究旨在确定镉（Cd）对鼓蚶繁殖期（产卵前）雌雄性腺中主要必需的ω-3 脂肪酸（二十碳五烯酸（EPA；C20:5n-3）和二十二碳六烯酸（DHA；C22:6n-3）变化的影响。此外，本工作还试图描述 EPA 和 DHA 与非亚甲基中断二烯酸（NMID）脂肪酸之间的关系，并探讨它们对镉应激的可能保护作用。在 El Battah 采集了样本，这是一个相对清洁的海滩，并在实验室中进行了养殖。测量了温度、pH 值、盐度和溶解氧等理化参数。在养殖水中添加了两种亚致死浓度（LC 和 LC-96h，此前已确定）的 Cd。双因素方差分析表明，两种脂肪酸的浓度和性别都有显著影响。我们的结果表明，EPA 和 DHA 在两性中的浓度都显著降低，而雌性中的影响更强。两性的 NMID 脂肪酸与两种必需的 ω-3 脂肪酸之间也存在负相关。
