Morinaga Takeshi, Imai Katsunori, Yamashita Yo-Ichi, Yamao Takanobu, Kaida Takayoshi, Nakagawa Shigeki, Hashimoto Daisuke, Chikamoto Akira, Sumiyoshi Shinji, Mikami Yoshiki, Baba Hideo
a Department of Gastroenterological Surgery, Graduate School of Life Sciences , Kumamoto University , Kumamoto , Japan.
b Department of Diagnostic Pathology , Kumamoto University Hospital , Kumamoto , Japan.
Scand J Gastroenterol. 2017 Aug;52(8):916-919. doi: 10.1080/00365521.2017.1322140. Epub 2017 May 9.
Multicystic biliary hamartoma (MCBH) is a rare cystic disease of the liver. We herein report a case of MCBH associated with extremely elevated levels of serum carbohydrate antigen (CA) 19-9. A 53-year-old man was referred to our hospital because of extremely elevated CA19-9 levels (more than 12,000 U/mL). Enhanced abdominal computed tomography and magnetic resonance imaging (MRI) revealed a multicystic tumor with a calcified wall in the left lobe of the liver, although no apparent intracystic nodule was detected. Because of the possibility of a malignant tumor, such as intraductal papillary neoplasm of the bile duct or cystadenocarcinoma, the patient underwent left hepatectomy. Based on the postoperative pathological findings, the lesion was diagnosed as MCBH. The serum CA19-9 level drastically decreased after surgery. We encountered a rare case of MCBH with extremely elevated CA19-9 levels.
多囊性胆管错构瘤（MCBH）是一种罕见的肝脏囊性疾病。我们在此报告一例与血清糖类抗原（CA）19-9水平极度升高相关的MCBH病例。一名53岁男性因CA19-9水平极度升高（超过12,000 U/mL）转诊至我院。增强腹部计算机断层扫描和磁共振成像（MRI）显示肝左叶有一个壁钙化的多囊性肿瘤，尽管未检测到明显的囊内结节。由于存在胆管内乳头状肿瘤或囊腺癌等恶性肿瘤的可能性，患者接受了左肝切除术。根据术后病理结果，该病变被诊断为MCBH。术后血清CA19-9水平急剧下降。我们遇到了一例CA19-9水平极度升高的罕见MCBH病例。
