• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

昼夜节律:神经元让道——神经胶质细胞介导 SCN 时钟功能。

Circadian Rhythms: Move Over Neurons - Astrocytes Mediate SCN Clock Function.

机构信息

Divisions of Perinatal Biology and Immunobiology, Perinatal Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, USA.

Divisions of Perinatal Biology and Immunobiology, Perinatal Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, USA.

出版信息

Curr Biol. 2017 May 8;27(9):R350-R352. doi: 10.1016/j.cub.2017.03.055.

DOI:10.1016/j.cub.2017.03.055
PMID:28486120
Abstract

Neurons in the suprachiasmatic nuclei (SCN) of the hypothalamus are described as master pacemaker cells for biological rhythms. However, a series of recent studies demonstrate the importance of another cell type, astrocytes, for biological timekeeping.

摘要

下丘脑视交叉上核(SCN)中的神经元被描述为生物节律的主起搏器细胞。然而,最近的一系列研究表明,另一种细胞类型——星形胶质细胞,对生物钟计时也很重要。

相似文献

1
Circadian Rhythms: Move Over Neurons - Astrocytes Mediate SCN Clock Function.昼夜节律:神经元让道——神经胶质细胞介导 SCN 时钟功能。
Curr Biol. 2017 May 8;27(9):R350-R352. doi: 10.1016/j.cub.2017.03.055.
2
Astrocytes Regulate Daily Rhythms in the Suprachiasmatic Nucleus and Behavior.星形胶质细胞调节视交叉上核的昼夜节律和行为。
Curr Biol. 2017 Apr 3;27(7):1055-1061. doi: 10.1016/j.cub.2017.02.037. Epub 2017 Mar 23.
3
Astrocytic Modulation of Neuronal Activity in the Suprachiasmatic Nucleus: Insights from Mathematical Modeling.星形胶质细胞对视交叉上核神经元活动的调节:数学建模的见解。
J Biol Rhythms. 2020 Jun;35(3):287-301. doi: 10.1177/0748730420913672. Epub 2020 Apr 14.
4
Calcium Circadian Rhythmicity in the Suprachiasmatic Nucleus: Cell Autonomy and Network Modulation.视交叉上核中的钙昼夜节律:细胞自主性和网络调节。
eNeuro. 2017 Aug 18;4(4). doi: 10.1523/ENEURO.0160-17.2017. eCollection 2017 Jul-Aug.
5
Entrainment of circadian clocks in mammals by arousal and food.觉醒和食物对哺乳动物生物钟的同步作用。
Essays Biochem. 2011 Jun 30;49(1):119-36. doi: 10.1042/bse0490119.
6
The suprachiasmatic nucleus: a 25-year retrospective.视交叉上核:25年回顾
J Biol Rhythms. 1998 Apr;13(2):100-12. doi: 10.1177/074873098128999952.
7
Astrocytes Sustain Circadian Oscillation and Bidirectionally Determine Circadian Period, But Do Not Regulate Circadian Phase in the Suprachiasmatic Nucleus.星形胶质细胞维持昼夜节律振荡并双向决定昼夜节律周期,但不调节视交叉上核中的昼夜节律相位。
J Neurosci. 2022 Jul 13;42(28):5522-5537. doi: 10.1523/JNEUROSCI.2337-21.2022.
8
Clock controls circadian period in isolated suprachiasmatic nucleus neurons.生物钟控制孤立的视交叉上核神经元的昼夜节律周期。
Nat Neurosci. 1998 Dec;1(8):708-13. doi: 10.1038/3708.
9
Synchronisation mechanisms of circadian rhythms in the suprachiasmatic nucleus.视交叉上核中昼夜节律的同步机制。
IET Syst Biol. 2009 Mar;3(2):100-12. doi: 10.1049/iet-syb.2007.0057.
10
Localization and expression of GABA transporters in the suprachiasmatic nucleus.γ-氨基丁酸转运体在视交叉上核中的定位与表达
Eur J Neurosci. 2015 Dec;42(12):3018-32. doi: 10.1111/ejn.13083. Epub 2015 Dec 8.

引用本文的文献

1
Astrocyte regulation of behavioral outputs: the versatile roles of calcium.星形胶质细胞对行为输出的调节:钙的多种作用
Front Cell Neurosci. 2025 May 15;19:1606265. doi: 10.3389/fncel.2025.1606265. eCollection 2025.
2
Chronobioethics: Symphony of biological clocks observed by 7-day/24-h ambulatory blood pressure monitoring and cardiovascular health.时间生物伦理学:通过7天/24小时动态血压监测和心血管健康观察生物钟的交响曲。
Biomed J. 2025 Jun;48(3):100753. doi: 10.1016/j.bj.2024.100753. Epub 2024 Jun 19.
3
Circadian cycle and neuroinflammation.
昼夜节律周期与神经炎症。
Open Life Sci. 2023 Oct 17;18(1):20220712. doi: 10.1515/biol-2022-0712. eCollection 2023.
4
Unconscious mind activates central cardiovascular network and promotes adaptation to microgravity possibly anti-aging during 1-year-long spaceflight.无意识的大脑激活中心心血管网络,并促进适应微重力,可能在为期 1 年的太空飞行中抗衰老。
Sci Rep. 2022 Jul 13;12(1):11862. doi: 10.1038/s41598-022-14858-8.
5
Astrocytic Modulation of Neuronal Activity in the Suprachiasmatic Nucleus: Insights from Mathematical Modeling.星形胶质细胞对视交叉上核神经元活动的调节:数学建模的见解。
J Biol Rhythms. 2020 Jun;35(3):287-301. doi: 10.1177/0748730420913672. Epub 2020 Apr 14.
6
Circadian rhythm and sleep-wake systems share the dynamic extracellular synaptic milieu.昼夜节律和睡眠-觉醒系统共享动态的细胞外突触微环境。
Neurobiol Sleep Circadian Rhythms. 2018 Apr 17;5:15-36. doi: 10.1016/j.nbscr.2018.04.001. eCollection 2018 Jun.
7
Resolving Astrocyte Heterogeneity in the CNS.解析中枢神经系统中的星形胶质细胞异质性
Front Cell Neurosci. 2017 Sep 27;11:300. doi: 10.3389/fncel.2017.00300. eCollection 2017.