线粒体动态平衡：联会蛋白二聚体如何介导线粒体融合？
Mitochondrial Homeostasis: How Do Dimers of Mitofusins Mediate Mitochondrial Fusion?
机构信息
Max-Delbrück Centrum für Molekulare Medizin, Crystallography Robert-Rössle-Strasse 10, 13125 Berlin, Germany; Freie Universität Berlin, Institute of Chemistry and Biochemistry, Takustraße 6, 14195 Berlin, Germany.
University of Geneva, Department of Biochemistry, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland; Swiss National Centre for Competence in Research Programme Chemical Biology, CH-1211 Geneva, Switzerland.
出版信息
Curr Biol. 2017 May 8;27(9):R353-R356. doi: 10.1016/j.cub.2017.03.024.
Mitochondria have high fusion and fission rates to maintain their size and number throughout the cell cycle. How is fusion mediated? New structural studies propose mechanisms by which the dynamin-like mitofusin proteins promote fusion of mitochondria.
线粒体具有较高的融合和裂变速率，以在整个细胞周期中维持其大小和数量。融合是如何介导的？新的结构研究提出了驱动蛋白样线粒融合蛋白促进线粒体融合的机制。
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