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热性惊厥患者的评估:危险因素、复发、治疗与预后

Evaluation of Patients With Febrile Seizure: Risk Factors, Reccurence, Treatment and Prognosis.

作者信息

Renda Rahime, Yüksel Deniz, Gürer Y K Yavuz

机构信息

From the Antalya Research and Education Hospital, Pediatric and Pediatric Nephrology Department, Antalya, Turkey.

Sami Ulus Research and Training Hospital, Pediatric Neurology Department.

出版信息

Pediatr Emerg Care. 2020 Apr;36(4):173-177. doi: 10.1097/PEC.0000000000001173.

DOI:10.1097/PEC.0000000000001173
PMID:28486267
Abstract

INTRODUCTION

Febrile convulsion (FC) is the most common neurological disorder in childhood. The aim of this study was to determine the risk factors for recurrence and the development of epilepsy from the demographic data of these patients.

METHODS

A retrospective study was made of 680 patients with FC who presented to our hospital. Patients with only FC were defined as group 1 and those who developed epilepsy after FC as group 2. Comparisons were made between the 2 groups of the demographic parameters, parental consanguinity, familial history of FCs or epilepsy, criteria for starting prophylactic treatment, response to treatment, risk factors for recurrence, and results of electroencephalogram.

RESULTS

The study included a total of 680 patients comprising 399 males (59%) and 281 females (41%). A diagnosis of FC was made in 652 cases (95.8%, group 1), and epilepsy was diagnosed in 28 (4.2%, group 2). A positive familial history of FCs was determined statistically significantly higher in group 1. On the other hand, a history of pathological birth and parental consanguinity was found higher in group 2. Prophylactic treatment was administered to 89.3% of group 2 and 40.3% of group 1.

CONCLUSIONS

Febrile convulsions create fear and panic in the family and are a significant health problem in Turkey. The conclusion that has been reached is that the unnecessary administration of prophylactic treatment could be prevented with education of the families on the subject of fever and correct identification of patients at risk of developing epilepsy.

摘要

引言

热性惊厥(FC)是儿童期最常见的神经系统疾病。本研究的目的是根据这些患者的人口统计学数据确定复发风险因素以及癫痫的发生情况。

方法

对我院收治的680例热性惊厥患者进行回顾性研究。仅患有热性惊厥的患者定义为第1组,热性惊厥后发生癫痫的患者定义为第2组。比较两组的人口统计学参数、父母近亲结婚情况、热性惊厥或癫痫家族史、开始预防性治疗的标准、治疗反应、复发风险因素以及脑电图结果。

结果

该研究共纳入680例患者,其中男性399例(59%),女性281例(41%)。652例(95.8%,第1组)诊断为热性惊厥,28例(4.2%,第2组)诊断为癫痫。第1组中热性惊厥家族史阳性在统计学上显著更高。另一方面,第2组中病理性出生史和父母近亲结婚情况更高。第2组89.3%的患者和第1组40.3%的患者接受了预防性治疗。

结论

热性惊厥在家庭中引发恐惧和恐慌,在土耳其是一个重要的健康问题。得出的结论是,通过对家庭进行发热主题教育以及正确识别有癫痫发作风险的患者,可以避免不必要的预防性治疗。

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