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[从汞矿分离出的细菌中汞抗性决定因子的核苷酸序列:在不动杆菌属物种质粒中检测到一个重组汞转座子家族]

[Nucleotide sequences of mercury resistance determinants in bacteria isolated from mercury mines: detection of a family of recombinant mercury transposons in plasmids from Acinetobacter species].

作者信息

Lomovskaia O L, Nikiforov V G

出版信息

Genetika. 1988 Sep;24(9):1539-49.

PMID:2848749
Abstract

Partial nucleotide sequences were determined for mer operons located on large and small plasmids previously described in Acinetobacter spp. isolated from different mercury mines of the USSR. Inspection of the sequences shows that: 1. All Acinetobacter mer operons studied belong to a family of transposons homologous to transposons found in clinical isolates. 2. The transposons located on the small plasmids originated by recombinations between the transposons from the large plasmids and Tn501, a transposon found in a Pseudomonas hospital strain isolated in Australia. The left arm of each hybrid transposon was donated by a transposon of a large Acinetobacter plasmid and the right arm - by the Tn501.

摘要

测定了先前在苏联不同汞矿分离出的不动杆菌属中发现的大质粒和小质粒上mer操纵子的部分核苷酸序列。对这些序列的检查表明:1. 所有研究的不动杆菌mer操纵子都属于一个转座子家族,该家族与临床分离株中发现的转座子同源。2. 位于小质粒上的转座子是由大质粒上的转座子与Tn501(在澳大利亚分离的一株假单胞菌医院菌株中发现的转座子)之间的重组产生的。每个杂种转座子的左臂由一个大不动杆菌质体的转座子提供,右臂由Tn501提供。

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