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与磷化铝中毒相关的可逆性心肌损伤和心室内血栓形成

Reversible Myocardial Injury and Intraventricular Thrombus Associated with Aluminium Phosphide Poisoning.

作者信息

El Hangouche Abdelkader Jalil, Fennich Hala, Alaika Oumaima, Dakka Taoufiq, Raissouni Zaineb, Oukerraj Latifa, Doghmi Nawal, Cherti Mohamed

机构信息

Laboratory of Physiology, Faculty of Medicine and Pharmacy of Tangier, Abdelmalek Essaâdi University, Tangier, Morocco.

Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.

出版信息

Case Rep Cardiol. 2017;2017:6287015. doi: 10.1155/2017/6287015. Epub 2017 Apr 9.

Abstract

Aluminium phosphide (ALP) is widely used as a fumigant pesticide. In case of ALP poisoning, it is responsible for myocardial dysfunction, related to toxic myocarditis, and hemodynamic disorders. We report a case of a 28-year-old female who had intentionally ingested ALP and was admitted with cardiogenic shock. The transthoracic echocardiography (TTE) at the time of admission showed severe global myocardial hypokinesia with the presence of a giant left ventricular thrombus. Cardiovascular magnetic resonance (CMR) revealed extensive toxic myocarditis with a left ventricular systolic dysfunction. All cardiac lesions were reversible after symptomatic treatment, within 6 months. We aim, by reporting this case, to evidence the complete reversibility of cardiac injury due to aluminium phosphide poisoning documented by transthoracic echocardiography and cardiovascular magnetic resonance.

摘要

磷化铝(ALP)被广泛用作熏蒸杀虫剂。在磷化铝中毒的情况下,它会导致与中毒性心肌炎相关的心肌功能障碍和血流动力学紊乱。我们报告一例28岁女性故意摄入磷化铝并因心源性休克入院的病例。入院时经胸超声心动图(TTE)显示严重的全心心肌运动减弱,并存在巨大的左心室血栓。心血管磁共振(CMR)显示广泛的中毒性心肌炎伴左心室收缩功能障碍。经过对症治疗,所有心脏病变在6个月内均可逆转。我们通过报告该病例,旨在证明经胸超声心动图和心血管磁共振记录的磷化铝中毒所致心脏损伤的完全可逆性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/446e/5401723/33141d02bc87/CRIC2017-6287015.001.jpg

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