Papatheodorou D C, Liakou C G, Kalogerakos K, Dimopoulos Johannes Carl Athanasios, Kalinoglou N
Department of Gynecology, Metaxa Cancer Hospital, Piraeus, Greece.
Breast Unit, Metaxa Cancer Hospital, Piraeus, Greece.
Case Rep Obstet Gynecol. 2017;2017:1357203. doi: 10.1155/2017/1357203. Epub 2017 Apr 12.
Vulvar carcinoma is a rare disease that accounts for 3-5% of all gynecologic malignancies. Breast represents an unusual site of metastasis and only a few cases are reported. We describe the first case of bilateral metastatic breast carcinoma of vulvar origin, at an 80-year-old female patient. Six months after treatment of her primary disease, she presented with bilateral metastatic squamous cell breast carcinoma. Diagnosis was based on clinical, radiological, and histological facts. Breast although rare is another potential site of metastasis in vulvar cancer and thus mammary gland examination should be considered in the follow-up of these patients. Differential diagnosis between primary and metastatic lesions is of utmost importance for appropriate management.
外阴癌是一种罕见疾病,占所有妇科恶性肿瘤的3%至5%。乳腺是不常见的转移部位,仅有少数病例报道。我们描述了首例源自外阴的双侧转移性乳腺癌,患者为一名80岁女性。在其原发性疾病治疗6个月后,她出现了双侧转移性鳞状细胞乳腺癌。诊断基于临床、影像学和组织学依据。乳腺虽罕见,但也是外阴癌另一个潜在的转移部位,因此在这些患者的随访中应考虑进行乳腺检查。对于恰当的治疗管理而言,原发性病变与转移性病变之间的鉴别诊断至关重要。