Department of Radiology (Services), Okayama Saiseikai General Hospital, 2-25 Kokutai-cho, Kita-ku, Okayama-Shi, Okayama, 700-8511, Japan.
Department of Radiology, Okayama Saiseikai General Hospital, 2-25 Kokutai-cho, Kita-ku, Okayama-shi, Okayama, 700-8511, Japan.
Abdom Radiol (NY). 2017 Oct;42(10):2571-2578. doi: 10.1007/s00261-017-1163-y.
To evaluate the usefulness of a novel contrast-injection protocol for high-resolution abdominal computed tomography angiography (CTA) using nitroglycerin (NTG).
Abdominal CTA was performed in 80 patients using two 64-detector-row CT scanners. Forty patients were examined after administration of sublingual NTG (NTG group), while 40 were examined without NTG administration (non-NTG group). Arterial phase images were acquired with maximum intensity projection and volume rendering. Reduction rates: vessel cross-sectional areas ratio of 10 cm distal to origin at the superior mesenteric artery, contrast enhancements, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were assessed. Three reviewers evaluated degree of depiction of the peripancreatic vasculature using a four-point scale (1 = poor, 4 = excellent).
Reduction rates were significantly lower in the NTG group (P < 0.001), while there were no significant differences in contrast enhancements, SNR, or CNR between groups. Visual evaluation results of the NTG group were significantly better than those of the non-NTG group (P < 0.01).
Abdominal CTA using NTG improved visualization of the abdominal peripheral vessels. This improved arterial view may be beneficial for preoperative evaluation of the arterial anatomy.
评估使用硝化甘油（NTG）的新型腹部高分辨率 CT 血管造影（CTA）对比注射方案的有效性。
使用两台 64 排 CT 扫描仪对 80 例患者进行腹部 CTA 检查。40 例患者在舌下给予 NTG 后进行检查（NTG 组），而 40 例患者在未给予 NTG 情况下进行检查（非 NTG 组）。采用最大密度投影和容积再现获取动脉期图像。评估血管截面积比：肠系膜上动脉起源处 10cm 处的血管截面积比、对比增强、信噪比（SNR）和对比噪声比（CNR）。三位审阅者使用四点量表（1=差，4=优）评估胰周血管的显影程度。
NTG 组的血管截面积比明显较低（P<0.001），而两组之间的对比增强、SNR 或 CNR 没有显著差异。NTG 组的视觉评估结果明显优于非 NTG 组（P<0.01）。
腹部 CTA 使用 NTG 可改善腹部外周血管的可视化效果。这种动脉视图的改善可能有助于术前评估动脉解剖结构。
