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Bioengineering of an Intraabdominal Endocrine Pancreas.

作者信息

Baidal David A, Ricordi Camillo, Berman Dora M, Alvarez Ana, Padilla Nathalia, Ciancio Gaetano, Linetsky Elina, Pileggi Antonello, Alejandro Rodolfo

机构信息

University of Miami Leonard M. Miller School of Medicine, Miami, FL

出版信息

N Engl J Med. 2017 May 11;376(19):1887-1889. doi: 10.1056/NEJMc1613959.

DOI:10.1056/NEJMc1613959
PMID:28489987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5572072/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd3/5572072/99fc5e940190/nihms889800f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd3/5572072/99fc5e940190/nihms889800f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7dd3/5572072/99fc5e940190/nihms889800f1.jpg

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1
Bioengineering of an Intraabdominal Endocrine Pancreas.腹腔内分泌胰腺的生物工程
N Engl J Med. 2017 May 11;376(19):1887-1889. doi: 10.1056/NEJMc1613959.
2
[Islet transplantation for treatment of type-1 diabetes mellitus].
Cas Lek Cesk. 2011;150(1):49-55.
3
Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus.改进人类胰岛分离方法，用于一项关于1型糖尿病胰岛移植与最佳药物治疗的前瞻性队列研究。
Arch Surg. 2005 Aug;140(8):735-44. doi: 10.1001/archsurg.140.8.735.
4
Human islet transplantation in patients with type I diabetes.I型糖尿病患者的人胰岛移植。
Transplant Proc. 1989 Feb;21(1 Pt 3):2744-5.
5
Xenotransplantation of rat pancreatic endocrine cells in spontaneous and streptozotocin-induced diabetic monkeys.大鼠胰腺内分泌细胞在自发性和链脲佐菌素诱导的糖尿病猴中的异种移植。
Transplant Proc. 1989 Feb;21(1 Pt 3):2736-8.
6
[Current aspects of islet cell transplantation].[胰岛细胞移植的当前进展]
Med Klin (Munich). 1996 Feb 15;91 Suppl 1:19-24.
7
[Current status on transplantation of the endocrine pancreas in the treatment of diabetes mellitus. I. Transplantation of the islands of Langerhans].
Minerva Med. 1979 Jul 21;70(33):2295-307.
8
Fetal islet cell transplantation in China.中国的胎儿胰岛细胞移植。
Transplant Proc. 1989 Feb;21(1 Pt 3):2605-7.
9
[First experience in transplantation of cultured cells of human insuloma to patients with diabetes mellitus].[将人胰岛素瘤培养细胞移植到糖尿病患者体内的首次经验]
Klin Khir. 1995(11-12):28-30.
10
[Transplantation of cultured Langerhans cells of fetal pancreas in the treatment of insulin-dependent diabetes mellitus].[培养的胎儿胰腺朗格汉斯细胞移植治疗胰岛素依赖型糖尿病]
Biull Eksp Biol Med. 1994 Apr;117(4):356-63.

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The future of islet transplantation beyond the BLA approval: challenges and opportunities.胰岛移植在生物制品许可申请（BLA）获批后的未来：挑战与机遇
Front Transplant. 2025 Mar 7;4:1522409. doi: 10.3389/frtra.2025.1522409. eCollection 2025.
2
High-Yield Generation of Glucose-Responsive Pseudoislets From Murine Insulinoma Cells for Studies and Longitudinal Monitoring of Graft Survival .从小鼠胰岛素瘤细胞高效生成葡萄糖反应性伪胰岛用于移植存活的研究及纵向监测
Cell Transplant. 2025 Jan-Dec;34:9636897251315123. doi: 10.1177/09636897251315123.
3
Current Challenges in Pancreas and Islet Transplantation: A Scoping Review.

本文引用的文献

1
Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia.1型糖尿病合并严重低血糖患者人胰岛移植3期试验
Diabetes Care. 2016 Jul;39(7):1230-40. doi: 10.2337/dc15-1988. Epub 2016 Apr 18.
2
Validation of the BETA-2 Score: An Improved Tool to Estimate Beta Cell Function After Clinical Islet Transplantation Using a Single Fasting Blood Sample.BETA-2评分的验证：一种使用单一空腹血样估计临床胰岛移植后β细胞功能的改良工具。
Am J Transplant. 2016 Sep;16(9):2704-13. doi: 10.1111/ajt.13807. Epub 2016 Apr 21.
3
Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold.
胰腺和胰岛移植的当前挑战：一项范围综述
Biomedicines. 2024 Dec 15;12(12):2853. doi: 10.3390/biomedicines12122853.
4
Biotechnology Revolution Shaping the Future of Diabetes Management.生物技术革命塑造糖尿病管理的未来。
Biomolecules. 2024 Dec 7;14(12):1563. doi: 10.3390/biom14121563.
5
Alternative therapeutic strategies in diabetes management.糖尿病管理中的替代治疗策略。
World J Diabetes. 2024 Jun 15;15(6):1142-1161. doi: 10.4239/wjd.v15.i6.1142.
6
Pancreatic islet transplantation: current advances and challenges.胰岛移植：当前的进展和挑战。
Front Immunol. 2024 Jun 3;15:1391504. doi: 10.3389/fimmu.2024.1391504. eCollection 2024.
7
Strategy for Clinical Setting of Co-transplantation of Mesenchymal Stem Cells and Pancreatic Islets.间质干细胞与胰岛共移植的临床策略。
Cell Transplant. 2024 Jan-Dec;33:9636897241259433. doi: 10.1177/09636897241259433.
8
Phase-changing citrate macromolecule combats oxidative pancreatic islet damage, enables islet engraftment and function in the omentum.相变柠檬酸盐大分子可对抗氧化胰岛损伤，促进胰岛在大网膜中的植入和功能。
Sci Adv. 2024 Jun 7;10(23):eadk3081. doi: 10.1126/sciadv.adk3081.
9
Current status of stem cell therapy for type 1 diabetes: a critique and a prospective consideration.1 型糖尿病干细胞治疗的现状：批判与前瞻性思考。
Stem Cell Res Ther. 2024 Jan 29;15(1):23. doi: 10.1186/s13287-024-03636-0.
10
Encapsulated stem cell-derived β cells exert glucose control in patients with type 1 diabetes.包被的干细胞衍生β细胞在 1 型糖尿病患者中发挥血糖控制作用。
Nat Biotechnol. 2024 Oct;42(10):1507-1514. doi: 10.1038/s41587-023-02055-5. Epub 2023 Nov 27.
生物工程化内分泌胰腺：在生物可吸收支架内进行网膜内胰岛移植。
Diabetes. 2016 May;65(5):1350-61. doi: 10.2337/db15-1525. Epub 2016 Feb 25.
4
Alternative transplantation sites for pancreatic islet grafts.胰岛移植物的替代移植部位。
Curr Diab Rep. 2011 Oct;11(5):364-74. doi: 10.1007/s11892-011-0216-9.
5
Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold.植入可生物降解支架网膜袋内的非人灵长类动物胰岛的长期存活。
Am J Transplant. 2009 Jan;9(1):91-104. doi: 10.1111/j.1600-6143.2008.02489.x.