Department of Psychology, University of Bologna, Bologna, Italy.
Psychother Psychosom. 2017;86(3):134-140. doi: 10.1159/000458458. Epub 2017 May 11.
The aim of this critical review was to outline emerging trends and perspectives of clinical pharmacopsychology, an area of clinical psychology that is concerned with the psychological effects of medications. The historical development of clinical pharmacopsychology is outlined, with discussion of its most representative expressions and reference to current challenges of clinical research, with particular reference to clinimetrics. The domains of clinical pharmacopsychology encompass the clinical benefits of psychotropic drugs, the characteristics that predict responsiveness to treatment, the vulnerabilities induced by treatment (side effects, behavioral toxicity, iatrogenic comorbidity), and the interactions between drug treatment and psychological variables. Its aim is to provide a comprehensive assessment of the clinical important changes that are concerned with (a) wanted and expected treatment effects, (b) treatment-induced unwanted side effects, and (c) the patient's own personal experience of a change in terms of well-being and/or quality of life. Clinical pharmacopsychology offers a unifying framework for the understanding of clinical phenomena in medical and psychiatric settings. Research in this area deserves high priority.
本次批判性评论的目的是概述临床精神药理学（临床心理学的一个分支，主要关注药物的心理效应）的新兴趋势和观点。本文概述了临床精神药理学的历史发展，讨论了其最具代表性的表现形式，并提到了当前临床研究的挑战，特别提到了临床计量学。临床精神药理学的领域包括精神药物的临床获益、预测治疗反应的特征、治疗引起的脆弱性（副作用、行为毒性、医源性共病），以及药物治疗与心理变量之间的相互作用。其目的是对与以下方面有关的临床重要变化进行全面评估：（a）期望和预期的治疗效果，（b）治疗引起的不良反应，以及（c）患者自身在幸福感和/或生活质量方面变化的个人体验。临床精神药理学为理解医学和精神病学环境中的临床现象提供了一个统一的框架。该领域的研究应得到高度重视。
