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颅骨朗格汉斯细胞组织细胞增生症(嗜酸性肉芽肿)模拟钱币性头痛。两例报告。

Langerhans cell histiocytosis (eosinophilic granuloma) of the skull mimicking nummular headache. Report of two cases.

机构信息

1 Department of Neurology & Neurosurgery, Clinical Hospital of University of Chile, Santiago de Chile, Chile.

2 Clinical Neurosciences, Royal Free London NHS Foundation Trust, London, UK.

出版信息

Cephalalgia. 2018 Apr;38(4):794-797. doi: 10.1177/0333102417708772. Epub 2017 May 10.

DOI:10.1177/0333102417708772
PMID:28490189
Abstract

Background Nummular headache is a rare, recently described topographic headache defined by the circumscribed coin-shaped area of pain. It is classified as a primary headache. There is debate about whether it is due to a peripheral or central disturbance, and its relationship to migraine. Case reports We report two patients with presumed nummular headache secondary to Langerhans cell histiocytosis, both with resolution of their headaches after surgical resection. Conclusion Imaging in patients with clinical features of nummular headache is recommended, as this and other cases highlight that it may be symptomatic. There are no distinguishing clinical features to separate nummular headache from secondary mimics, and treatment of the underlying cause may be curative.

摘要

背景 钱币状头痛是一种罕见的、最近描述的局灶性头痛,其特征为疼痛呈局限性硬币状。它被归类为原发性头痛。关于它是由周围还是中枢紊乱引起的,以及它与偏头痛的关系,存在争议。 病例报告 我们报告了两例由朗格汉斯细胞组织细胞增生症引起的疑似钱币状头痛患者,均通过手术切除后头痛缓解。 结论 建议对具有钱币状头痛临床特征的患者进行影像学检查,因为这和其他病例强调了它可能是症状性的。没有明显的临床特征可以将钱币状头痛与继发性类似物区分开来,而治疗潜在病因可能是治愈性的。

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Zhongguo Dang Dai Er Ke Za Zhi. 2025 May 15;27(5):555-562. doi: 10.7499/j.issn.1008-8830.2412173.
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Nummular Headache and Its Surgical Treatment.钱币状头痛及其外科治疗
Plast Reconstr Surg Glob Open. 2020 Jul 28;8(7):e2989. doi: 10.1097/GOX.0000000000002989. eCollection 2020 Jul.
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Nummular Headache.钱币状头痛。
Curr Neurol Neurosci Rep. 2019 Apr 17;19(6):26. doi: 10.1007/s11910-019-0943-x.
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Clinical characteristics of nummular headache and differentiation between spontaneous and posttraumatic variant: an observational study.临床特征的硬币形头痛和区分自发性和外伤性变异:一项观察性研究。
J Headache Pain. 2019 Apr 8;20(1):34. doi: 10.1186/s10194-019-0981-4.