Jefferson Headache Center, 900 Walnut Street, Suite 200, Philadelphia, PA, USA.
Curr Neurol Neurosci Rep. 2019 Apr 17;19(6):26. doi: 10.1007/s11910-019-0943-x.
This article reviews nummular headache (NH), including the latest literature on the epidemiological and clinical features, the most recent proposed pathophysiology, and novel management.
NH is characterized by continuous or intermittent head pain confined to a focal circumscribed area (1-6 cm in diameter). It is usually of mild to moderate intensity, although some patients have severe continuous pain or disabling exacerbations. NH is a primary headache, though many secondary cases have been described. Evaluation requires exclusion of systemic and structural diseases. Gabapentin can be recommended as a first-line preventive treatment. If poorly tolerated or in refractory cases, botulinum toxin is a reasonable alternative. NH is a fairly common disorder in patients presenting to a headache clinic. Increased understanding of NH will lead to improved outcomes. Clinical trials would lead to enhanced knowledge of NH.
本文综述钱币状头痛(NH),包括流行病学和临床特征的最新文献、最近提出的病理生理学和新的治疗方法。
NH 的特征是局限于局灶性、有界区域(直径 1-6 厘米)的持续或间歇性头痛。它通常是轻度到中度强度,尽管一些患者有严重的持续疼痛或致残性加重。NH 是一种原发性头痛,但也有许多继发性病例。评估需要排除系统性和结构性疾病。加巴喷丁可作为一线预防治疗药物。如果不能耐受或难治性病例,肉毒毒素是一种合理的替代治疗。NH 在头痛诊所就诊的患者中较为常见。对 NH 的认识提高将导致预后改善。临床试验将提高对 NH 的认识。