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人工耳蜗电极密封技术及相关的耳蜗内压力变化

Cochlear implant electrode sealing techniques and related intracochlear pressure changes.

作者信息

Todt Ingo, Utca Julica, Karimi Dania, Ernst Arne, Mittmann Philipp

机构信息

Department of Otolaryngology, Head and Neck Surgery, Unfallkrankenhaus Berlin, Warenerstr.7, 12683, Berlin, Germany.

出版信息

J Otolaryngol Head Neck Surg. 2017 May 11;46(1):40. doi: 10.1186/s40463-017-0218-y.

DOI:10.1186/s40463-017-0218-y
PMID:28490377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5426068/
Abstract

BACKGROUND

The inserted cochlear implanted electrode is covered at the site of the round window or cochleostomy to prevent infections and leakage. In a surgically hearing preservational concept, low intracochlear pressure changes are of high importance. The aim of this study was to observe intracochlear pressure changes due to different sealing techniques in a cochlear model.

METHODS

Cochlear implant electrode insertions were performed in an artifical cochlear model and the intracochlear pressure changes were recorded in parallel with a micro-pressure sensor positioned in the apical region of the cochlea model to follow the maximum amplitude of intracochlear pressure. Four different sealing conditions were compared: 1) overlay, 2) overlay with fascia pushed in, 3) donut-like fascia ring, 4) donut-like fascia ring pushed in.

RESULTS

We found statistically significant differences in the occurrence of maximum amplitude of intracochlear pressure peak changes related to sealing procedure comparing the different techniques. While the lowest amplitude changes could be observed for the overlay technique (0.14 mmHg ± 0.06) the highest values could be observed for the donut-like pushed in technique (1.79 mmHg ± 0.69).

CONCLUSION

Sealing the electrode inserted cochlea can lead to significant intracochlear pressure changes. Pushing in of the sealing tissue cannot be recommended.

摘要

背景

植入的人工耳蜗电极在圆窗或耳蜗造口处进行覆盖,以防止感染和渗漏。在手术听力保留概念中,低耳蜗内压力变化至关重要。本研究的目的是观察耳蜗模型中不同密封技术引起的耳蜗内压力变化。

方法

在人工耳蜗模型中进行人工耳蜗电极植入,并使用位于耳蜗模型顶端区域的微压力传感器并行记录耳蜗内压力变化,以跟踪耳蜗内压力的最大幅度。比较了四种不同的密封条件:1)覆盖,2)推入筋膜覆盖,3)环形筋膜环,4)推入环形筋膜环。

结果

比较不同技术时,我们发现与密封程序相关的耳蜗内压力峰值变化最大幅度的发生存在统计学显著差异。虽然覆盖技术的幅度变化最低(0.14 mmHg±0.06),但推入环形筋膜环技术的幅度变化最高(1.79 mmHg±0.69)。

结论

密封插入电极的耳蜗会导致显著的耳蜗内压力变化。不建议将密封组织推入。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/468a2ff58c48/40463_2017_218_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/420f4d388444/40463_2017_218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/3343ee7af008/40463_2017_218_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/468a2ff58c48/40463_2017_218_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/420f4d388444/40463_2017_218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/3343ee7af008/40463_2017_218_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8089/5426068/468a2ff58c48/40463_2017_218_Fig3_HTML.jpg

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本文引用的文献

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Otolaryngol Head Neck Surg. 2017 Apr;156(4):712-716. doi: 10.1177/0194599816684104. Epub 2016 Dec 27.
2
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Biomed Res Int. 2016;2016:3937196. doi: 10.1155/2016/3937196. Epub 2016 Nov 9.
3
Comparison of the effects of four different cochlear implant electrodes on intra-cochlear pressure in a model.
四种不同人工耳蜗电极对模型中耳蜗内压力影响的比较。
Acta Otolaryngol. 2017 Mar;137(3):235-241. doi: 10.1080/00016489.2016.1232490. Epub 2016 Sep 23.
4
Hearing Preservation With a Midscalar Electrode Comparison of a Regular and Steroid/Pressure Optimized Surgical Approach in Patients With Residual Hearing.使用中阶电极保留听力:残余听力患者常规手术方法与类固醇/压力优化手术方法的比较
Otol Neurotol. 2016 Oct;37(9):e349-52. doi: 10.1097/MAO.0000000000001068.
5
Optimisation of the round window opening in cochlear implant surgery in wet and dry conditions: impact on intracochlear pressure changes.湿态和干态下人工耳蜗植入手术中圆窗开口的优化:对耳蜗内压力变化的影响
Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3609-3613. doi: 10.1007/s00405-016-3993-6. Epub 2016 Mar 18.
6
Insertion of Cochlear Implant Electrode Array Using the Underwater Technique for Preserving Residual Hearing.采用水下技术植入人工耳蜗电极阵列以保留残余听力
Otol Neurotol. 2016 Apr;37(4):339-44. doi: 10.1097/MAO.0000000000000989.
7
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Insertion site and sealing technique affect residual hearing and tissue formation after cochlear implantation.植入部位和密封技术会影响人工耳蜗植入后的残余听力和组织形成。
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