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[中间神经元突触后电位的定量分析:从噪声中恢复信号]

[Quantal analysis of the postsynaptic potentials in interneuronal synapses: the recovery of the signal from the noise].

作者信息

Bart A G, Ditiatev A E, Kozhanov V M

出版信息

Neirofiziologiia. 1988;20(4):479-87.

PMID:2849062
Abstract

Discrete distributions of the elementary EPSP amplitude in the interneuronal synapses of vertebrates were obtained by the maximum likelihood method. The equality of the intervals between values of the computed densities testifies to the quantal nature of the signal. The binomial model approximating the empirical distributions is revealed to be able to distinguish quantal levels of the nerve impulse transmission. These levels are conditioned by the structural organization of the interneuronal connections. Systematical differences between empirical distributions and the model necessitate generalization of the latter.

摘要

通过最大似然法获得了脊椎动物中间神经元突触中基本兴奋性突触后电位(EPSP)幅度的离散分布。计算密度值之间间隔的相等性证明了信号的量子性质。结果表明,近似经验分布的二项式模型能够区分神经冲动传递的量子水平。这些水平取决于中间神经元连接的结构组织。经验分布与模型之间的系统差异使得有必要对后者进行推广。

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