Hakim Arsany, Oertel Markus, Wiest Roland
University institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Freiburgstr. 10, CH-3010 Bern, Switzerland.
Department of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Radiol Case Rep. 2017 Jan 30;12(2):365-370. doi: 10.1016/j.radcr.2016.12.007. eCollection 2017 Jun.
Differentiation between infectious and neoplastic brain processes is crucial for treatment planning. Advanced magnetic resonance imaging techniques, such as diffusion, perfusion, susceptibility weighted imaging, and magnetic resonance spectroscopy, enhance the imaging differences between these two pathologies. However, despite the utilization of these advanced techniques, the pathologic process may be confound by atypical findings. Here, we report a case of an autistic patient with multiple brain lesions with diffusion weighted imaging, susceptibility weighted imaging, and perfusion patterns resembling features of a multicentric glioblastoma, which were confirmed surgically, neuropathologically, and bacteriologically as brain abscesses. We discuss the differentiation of these different entities in the light of advanced magnetic resonance imaging techniques.
区分感染性和肿瘤性脑病变对于治疗方案的制定至关重要。先进的磁共振成像技术,如扩散加权成像、灌注加权成像、磁敏感加权成像和磁共振波谱分析,可增强这两种病理状态之间的影像差异。然而,尽管使用了这些先进技术,非典型表现仍可能混淆病理过程。在此,我们报告一例自闭症患者,其脑部有多个病变,扩散加权成像、磁敏感加权成像和灌注模式类似于多中心胶质母细胞瘤的特征,但经手术、神经病理学和细菌学证实为脑脓肿。我们根据先进的磁共振成像技术讨论这些不同实体的鉴别诊断。