注射A型肉毒杆菌毒素治疗慢性肛裂和肛门括约肌痉挛可改善隐性营养不良性大疱性表皮松解症患者的生活质量。
Botulinum toxin A injection for chronic anal fissures and anal sphincter spasm improves quality of life in recessive dystrophic epidermolysis bullosa.
作者信息
Chaptini Cassandra, Casey Genevieve, Harris Adam G, Wattchow David, Gordon Lynne, Murrell Dedee F
机构信息
Flinders Medical Centre, Adelaide, Australia.
Women's and Children's Hospital, Adelaide, Australia.
出版信息
Int J Womens Dermatol. 2015 Oct 23;1(4):167-169. doi: 10.1016/j.ijwd.2015.08.002. eCollection 2015 Dec.
Abstract
We report a 20-year-old female with generalized, severe, recessive dystrophic epidermolysis bullosa who developed secondary chronic anal fissures. This resulted in anal sphincter spasm and severe, disabling pain. She was treated with five botulinum toxin A injections into the internal anal sphincter over a period of 2 years and gained marked improvement in her symptoms. This case demonstrates the successful use of botulinum toxin A injections to relieve anal sphincter spasm and fissuring, with long-term improvement.
摘要
我们报告一名20岁患有全身性、重度隐性营养不良性大疱性表皮松解症的女性，她出现了继发性慢性肛裂。这导致肛门括约肌痉挛和严重的、致残性疼痛。在2年的时间里，她接受了5次肉毒杆菌毒素A注射到肛门内括约肌，症状得到了显著改善。该病例证明了肉毒杆菌毒素A注射在缓解肛门括约肌痉挛和肛裂方面的成功应用，并带来了长期改善。
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