Šimić Dubravka, Penavić Jasna Zeljko, Babić Dragan, Gunarić Anita
School of Medicine, University of Mostar, Kneza Branimira 11, 88000 Mostar, Bosnia and Herzegovina,
Psychiatr Danub. 2017 May;29(Suppl 2):104-110.
The acne patients are at higher risk of acquiring depresion and anxiety, which can lead to reduced quality of life. Effective treatment of acne can reduce symptoms of anxiety and depression and significantly improve other physiological parameters and quality of life of these patients. The aim of this study was to determine the psychological status and quality of life of acne patients before, during and after the treatment with oral isotretinoin.
The prospective study included a total of 127 patients suffering from moderate to severe form of acne. To assess the psychological status and quality of life of studied groups the following standard psychometric questionnaires were performed before, during and after the treatment with oral isotretinoin: Beck Depression Inventory (BDI), Assessments of the Psychological and Social Effects of Acne (APSEA), State Trait Anxiety Inventory (STAI), Measure of Psychological Stress (MPS) and Dermatology Specific Quality of Life (DSQL).
Results of the present study indicate that there is no increase in depressive and anxiety symptoms in the patients treated with oral isotretinoin. The psychological status by gender has shown the existence of differences between the genders in all measures of psychological status. Statistically significantly better quality of life was observed after healing than before treatment.
The results of our study showed no higher risk of depression and anxiety within the patients with acne treated with oral isotretinoin. Improvement of quality of life after the treatment of acne with oral isotretinoin was confirmed.
痤疮患者患抑郁症和焦虑症的风险更高，这会导致生活质量下降。有效治疗痤疮可减轻焦虑和抑郁症状，并显著改善这些患者的其他生理参数和生活质量。本研究的目的是确定口服异维A酸治疗前、治疗期间和治疗后痤疮患者的心理状态和生活质量。
这项前瞻性研究共纳入了127例中重度痤疮患者。为了评估研究组的心理状态和生活质量，在口服异维A酸治疗前、治疗期间和治疗后使用了以下标准心理测量问卷：贝克抑郁量表（BDI）、痤疮心理和社会影响评估量表（APSEA）、状态-特质焦虑量表（STAI）、心理压力测量量表（MPS）和皮肤病特定生活质量量表（DSQL）。
本研究结果表明，口服异维A酸治疗的患者抑郁和焦虑症状没有增加。按性别划分的心理状态显示，在所有心理状态测量指标上，不同性别之间存在差异。愈合后观察到的生活质量在统计学上显著优于治疗前。
我们的研究结果表明，口服异维A酸治疗的痤疮患者发生抑郁和焦虑的风险没有更高。口服异维A酸治疗痤疮后生活质量得到改善得到了证实。
