DiMaggio Charles J, Avraham Jacob B, Lee David C, Frangos Spiros G, Wall Stephen P
Department of Surgery, Division of Acute Care and Trauma Surgery, New York University School of Medicine, New York, NY.
Department of Population Health, New York University School of Medicine, New York, NY.
Acad Emerg Med. 2017 Oct;24(10):1244-1256. doi: 10.1111/acem.13223. Epub 2017 Sep 27.
Injury-related morbidity and mortality is an important emergency medicine and public health challenge in the United States. Here we describe the epidemiology of traumatic injury presenting to U.S. emergency departments (EDs), define changes in types and causes of injury among the elderly and the young, characterize the role of trauma centers and teaching hospitals in providing emergency trauma care, and estimate the overall economic burden of treating such injuries.
We conducted a secondary retrospective, repeated cross-sectional study of the Nationwide Emergency Department Data Sample (NEDS), the largest all-payer ED survey database in the United States. Main outcomes and measures were survey-adjusted counts, proportions, means, and rates with associated standard errors (SEs) and 95% confidence intervals. We plotted annual age-stratified ED discharge rates for traumatic injury and present tables of proportions of common injuries and external causes. We modeled the association of Level I or II trauma center care with injury fatality using a multivariable survey-adjusted logistic regression analysis that controlled for age, sex, injury severity, comorbid diagnoses, and teaching hospital status.
There were 181,194,431 (SE = 4,234) traumatic injury discharges from U.S. EDs between 2006 and 2012. There was a mean year-to-year decrease of 143 (95% CI = -184.3 to -68.5) visits per 100,000 U.S. population during the study period. The all-age, all-cause case-fatality rate for traumatic injuries across U.S. EDs during the study period was 0.17% (SE = 0.001%). The case-fatality rate for the most severely injured averaged 4.8% (SE = 0.001%), and severely injured patients were nearly four times as likely to be seen in Level I or II trauma centers (relative risk = 3.9 [95% CI = 3.7 to 4.1]). The unadjusted risk ratio, based on group counts, for the association of Level I or II trauma centers with mortality was risk ratio = 4.9 (95% CI = 4.5 to 5.3); however, after sex, age, injury severity, and comorbidities were accounted for, Level I or II trauma centers were not associated with an increased risk of fatality (odds ratio = 0.96 [95% CI = 0.79 to 1.18]). There were notable changes at the extremes of age in types and causes of ED discharges for traumatic injury between 2009 and 2012. Age-stratified rates of diagnoses of traumatic brain injury increased 29.5% (SE = 2.6%) for adults older than 85 and increased 44.9% (SE = 1.3%) for children younger than 18. Firearm-related injuries increased 31.7% (SE = 0.2%) in children 5 years and younger. The total inflation-adjusted cost of ED injury care in the United States between 2006 and 2012 was $99.75 billion (SE = $0.03 billion).
Emergency departments are a sensitive barometer of the continuing impact of traumatic injury as an important cause of morbidity and mortality in the United States. Level I or II trauma centers remain a bulwark against the tide of severe trauma in the United States, but the types and causes of traumatic injury in the United States are changing in consequential ways, particularly at the extremes of age, with traumatic brain injuries and firearm-related trauma presenting increased challenges.
在美国,与损伤相关的发病率和死亡率是急诊医学和公共卫生面临的一项重大挑战。在此,我们描述了美国急诊科(ED)收治的创伤性损伤的流行病学情况,明确了老年人和年轻人损伤类型及原因的变化,阐述了创伤中心和教学医院在提供急诊创伤护理方面的作用,并估算了治疗此类损伤的总体经济负担。
我们对美国最大的全付费者急诊调查数据库——全国急诊科数据样本(NEDS)进行了二次回顾性重复横断面研究。主要结局指标和测量指标为经调查调整的计数、比例、均值及比率以及相关标准误(SE)和95%置信区间。我们绘制了按年龄分层统计的创伤性损伤年度急诊出院率,并列出常见损伤及外部原因的比例表。我们使用多变量调查调整逻辑回归分析,对年龄、性别、损伤严重程度、合并症诊断及教学医院状况进行控制,以此模拟一级或二级创伤中心护理与损伤死亡率之间的关联。
2006年至2012年期间,美国急诊科有181,194,431例(SE = 4,234)创伤性损伤出院病例。在研究期间,每10万美国人口的就诊人次平均每年减少143例(95% CI = -184.3至 -68.5)。研究期间,美国急诊科所有年龄段、所有原因导致的创伤性损伤病死率为0.17%(SE = 0.001%)。最严重受伤患者的病死率平均为4.8%(SE = 0.001%),且重伤患者在一级或二级创伤中心就诊的可能性几乎是其他中心的四倍(相对风险 = 3.9 [95% CI = 3.7至4.1])。基于病例数计算的一级或二级创伤中心与死亡率关联的未调整风险比为风险比 = 4.9(9�% CI = 4.5至5.3);然而,在考虑性别、年龄、损伤严重程度和合并症后,一级或二级创伤中心与死亡风险增加并无关联(优势比 = 0.96 [95% CI = 0.79至1.18])。2009年至2012年期间,不同年龄段急诊创伤性损伤出院的类型和原因有显著变化。85岁以上成年人创伤性脑损伤的年龄分层诊断率增加了29.5%(SE = 2.6%),18岁以下儿童增加了44.9%(SE = 1.3%)。5岁及以下儿童与枪支相关的损伤增加了31.7%(SE = 0.2%)。2006年至2012年期间,美国经通胀调整后的急诊损伤护理总费用为997.5亿美元(SE = 0.03亿美元)。
急诊科是创伤性损伤作为美国发病率和死亡率重要原因持续影响的一个敏感晴雨表。一级或二级创伤中心仍是美国抵御严重创伤浪潮的堡垒,但美国创伤性损伤的类型和原因正在发生重大变化,尤其是在年龄两端,创伤性脑损伤和与枪支相关的创伤带来了越来越大的挑战。