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植入式心脏复律除颤器患者的抑郁及相关因素

Depression and Associated Factors in Patients with Implantable Cardioverter-Defibrillators.

作者信息

Moshkani Farahani Maryam, Taghipour Mehrdad, Motalebi Mohsen, Bakhshian Ramezan, Shahverdi Ehsan, Taghipour Sovaid, Abdi Soheyla, Moradi Ramzan

机构信息

Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

出版信息

J Tehran Heart Cent. 2016 Oct 3;11(4):168-173.

PMID:28496507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5424845/
Abstract

Psychological problems such as depression constitute a dilemma that patients with the implantable cardioverter-defibrillator (ICD) usually encounter and may impact their quality of life. The purpose of this study was to evaluate the prevalence of depression among adults with the ICD and the relationship between depression and associated factors. Totally, 115 individuals with the ICD participated in this cross-sectional study in Tehran, Iran, and depression and other related risk factors were evaluated in them. Two questionnaires, one for demographic characteristics and the Beck Depression Inventory, were applied for data acquisition. The data were analyzed, and the factors associated with depression in the patients with the ICD were assessed. The mean age of the study population was 59.85 ± 11.46 years. Males comprised 88 (76.5%) and females 27 (23.5%) of the patients. The multivariate analysis on the 115 patients revealed that frequency of ICD shocks (OR = 1.08, 95%CI: 1.02 - 1.10), male sex (OR = 2.28, 95%CI: 1.027 - 5.07), more hospital admissions (OR = 1.19, 95%CI: 1.11 - 1.25), smoking cessation (OR = 9.8, 95%CI: 4.48 - 20.07), presence of ICD shocks (OR = 4.5, 95%CI: 2.45 - 7.38), dyslipidemia (OR = 2.8, 95%CI: 1.22 - 4.95), and family history of depression (OR = 6.4, 95%CI: 3.0 - 13.46) were significantly and independently associated with the Beck score classifications. These findings suggest that a poor psychosocial outcome in patients with the ICD may occur as a result of a variety of associated factors, most of which are predictable and preventable.

摘要

抑郁症等心理问题是植入式心脏复律除颤器(ICD)患者通常会遇到的困境,可能会影响他们的生活质量。本研究的目的是评估ICD成年患者中抑郁症的患病率以及抑郁症与相关因素之间的关系。共有115名ICD患者参与了在伊朗德黑兰进行的这项横断面研究,并对他们的抑郁症及其他相关危险因素进行了评估。使用两份问卷进行数据收集,一份用于收集人口统计学特征,另一份是贝克抑郁量表。对数据进行了分析,并评估了ICD患者中与抑郁症相关的因素。研究人群的平均年龄为59.85±11.46岁。患者中男性有88名(76.5%),女性有27名(23.5%)。对这115名患者的多变量分析显示,ICD电击次数(OR = 1.08,95%CI:1.02 - 1.10)、男性(OR = 2.28,95%CI:1.027 - 5.07)、更多的住院次数(OR = 1.19,95%CI:1.11 - 1.25)、戒烟(OR = 9.8,95%CI:4.48 - 20.07)、存在ICD电击(OR = 4.5,95%CI:2.45 - 7.38)、血脂异常(OR = 2.8,95%CI:1.22 - 4.95)以及抑郁症家族史(OR = 6.4,95%CI:3.0 - 13.46)与贝克评分分类显著且独立相关。这些发现表明,ICD患者不良的心理社会结局可能是由多种相关因素导致的,其中大多数是可预测和可预防的。

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本文引用的文献

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Factors influencing psychological status and quality of life in patients with implantable cardioverter-defibrillators.影响植入式心脏复律除颤器患者心理状态和生活质量的因素。
Neuro Endocrinol Lett. 2014;35 Suppl 1:54-8.
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Beyond ventricular fibrillation analysis: comprehensive waveform analysis for all cardiac rhythms occurring during resuscitation.超越室颤分析:对复苏期间出现的所有心律进行全面波形分析。
Resuscitation. 2014 Nov;85(11):1541-8. doi: 10.1016/j.resuscitation.2014.08.022. Epub 2014 Sep 4.
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Characteristics associated with anxiety, depressive symptoms, and quality-of-life in a large cohort of implantable cardioverter defibrillator recipients.在一个大型植入式心脏除颤器受者队列中,与焦虑、抑郁症状和生活质量相关的特征。
J Psychosom Res. 2014 Aug;77(2):122-7. doi: 10.1016/j.jpsychores.2014.05.007. Epub 2014 Jun 2.
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Changes in serum levels of brain derived neurotrophic factor and nerve growth factor-beta in schizophrenic patients before and after treatment.精神分裂症患者治疗前后血清脑源性神经营养因子和神经生长因子-β水平的变化。
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Depression and cardiac disease: epidemiology, mechanisms, and diagnosis.抑郁症与心脏病:流行病学、机制及诊断
Cardiovasc Psychiatry Neurol. 2013;2013:695925. doi: 10.1155/2013/695925. Epub 2013 Apr 7.
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Behavioral interventions in patients with an implantable cardioverter defibrillator: lessons learned and where to go from here?植入式心脏复律除颤器患者的行为干预:经验教训及未来方向?
Pacing Clin Electrophysiol. 2013 May;36(5):578-90. doi: 10.1111/pace.12108. Epub 2013 Feb 25.
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Gender disparities in quality of life and psychological disturbance in patients with implantable cardioverter-defibrillators.植入式心脏复律除颤器患者生活质量和心理困扰的性别差异。
Circ J. 2013;77(5):1158-65. doi: 10.1253/circj.cj-12-1116. Epub 2013 Jan 22.
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Long QT syndrome and dilated cardiomyopathy with SCN5A p.R1193Q polymorphism: cardioverter-defibrillator implantation at 27 months.长QT综合征与伴有SCN5A基因p.R1193Q多态性的扩张型心肌病:27个月时植入心脏复律除颤器
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A randomized controlled trial of cognitive behavior therapy tailored to psychological adaptation to an implantable cardioverter defibrillator.一项针对植入式心脏复律除颤器心理适应的认知行为疗法的随机对照试验。
Psychosom Med. 2011 Apr;73(3):226-33. doi: 10.1097/PSY.0b013e31820afc63. Epub 2011 Feb 14.
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Prevalence and persistence of depression in patients with implantable cardioverter defibrillator: a 2-year longitudinal study.植入式心脏复律除颤器患者中抑郁症的患病率及持续情况:一项为期2年的纵向研究。
Pacing Clin Electrophysiol. 2010 Dec;33(12):1455-61. doi: 10.1111/j.1540-8159.2010.02887.x. Epub 2010 Oct 14.