皮质类固醇对根管治疗后疼痛缓解的影响：一项系统评价。
Effect of Corticosteroids on Pain Relief Following Root Canal Treatment: A Systematic Review.
作者信息
Iranmanesh Foad, Parirokh Masoud, Haghdoost Ali Akbar, Abbott Paul V
机构信息
Department ofEndodontics, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Endodontology Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
出版信息
Iran Endod J. 2017 Spring;12(2):123-130. doi: 10.22037/iej.2017.26.
Abstract
INTRODUCTION
Post-operative pain and flare-up may occur in up to 58% of patients following root canal treatment. The aim was to conduct a systematic review and a possible meta-analysis to determine the effect of glucocorticosteroid (GCS) on pain following root canal treatment.
METHODS AND MATERIALS
Scopus, MEDLINE and CENTRAL databases were searched up to 30 January 2017 with broad key words. In addition, the reference lists in eligible papers and text books were hand-searched. Assessment of the eligibility of papers and data extraction were performed by two independent reviewers.
RESULTS
Of 9891 articles, 18 were recruited as eligible papers. Most of these papers showed pain reducing effect of GCS on post-endodontic pain. Because of wide heterogeneity among the recruited papers, it was not possible to perform meta-analysis.
CONCLUSION
Based on the results of this systematic review, there is a vast heterogeneity amongst articles regarding the use of GCS and their effect on post-operative pain after endodontic treatment. Further investigations with similar methods and materials are needed before meta-analysis on the effect of GCS on post-operative pain following root canal treatment can be performed
摘要
引言
根管治疗后，高达58%的患者可能会出现术后疼痛和炎症复发。本研究旨在进行系统评价及可能的荟萃分析，以确定糖皮质激素（GCS）对根管治疗后疼痛的影响。
方法与材料
截至2017年1月30日，使用宽泛的关键词检索了Scopus、MEDLINE和CENTRAL数据库。此外，还手动检索了符合条件的论文和教科书中的参考文献列表。由两名独立的评审人员对论文的合格性进行评估并提取数据。
结果
在9891篇文章中，有18篇被纳入为合格论文。这些论文大多显示GCS对根管治疗后疼痛有减轻作用。由于纳入的论文之间存在广泛的异质性，因此无法进行荟萃分析。
结论
基于本系统评价的结果，关于GCS的使用及其对根管治疗后术后疼痛的影响，各文章之间存在很大的异质性。在对GCS对根管治疗后术后疼痛的影响进行荟萃分析之前，需要采用类似的方法和材料进行进一步研究。
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