Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hopitals, Saveetha Institute of Medical and Technical Sciences, Chennai, 600077, Tamil Nadu, India.
Department of Conservative Dentistry and Endodontics, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.
BMC Oral Health. 2023 Aug 12;23(1):562. doi: 10.1186/s12903-023-03195-5.
Pain is usually subjective and thus it is challenging to describe its characteristics such as nature, intensity, and origin. Non-invasive methods such as assessing salivary alpha-amylase (SAA) may aid the practitioner to evaluate the pain intensity. Hence, the current study aimed to correlate the levels of SAA with the pain intensity in patients presenting with varied endodontic pain levels.
Sixty patients who presented with varied intensities of endodontic pain were selected for the present study out of which seven patients were excluded/dropped, leaving a total sample of fifty-five patients for assessment. Mandibular molar with symptomatic irreversible pulpitis without periapical pathology were included in the study. A 5ml of un-stimulated was obtained from the patients, following which the local anesthesia was administered. Root canal treatment was then performed and the pain scores at pre-operative and post-operative were recorded. Additionally, salivary samples were collected after emergency endodontic treatment and sent for sialochemical analysis. IBM.SPSS statistics software 23.0 was employed to assess the obtained data.
A statistically significant drop in the pain score (P < 0.001) and SAA levels (P < 0.001) were observed post-operatively in the contract to pre-operative state. A strong positive correlation was reported between SAA levels and pain scores in patients undergoing emergency endodontic treatment at both time intervals namely pre-operative (P < 0.001) and post-operative (P < 0.001).
The results of this preliminary showed a strong association between the pain score and SAA levels in patients undergoing an emergency endodontic treatment.
疼痛通常是主观的，因此描述其特征（如性质、强度和来源）具有挑战性。评估唾液α-淀粉酶（SAA）等非侵入性方法可能有助于从业者评估疼痛强度。因此，本研究旨在评估 SAA 水平与表现出不同程度牙髓痛患者的疼痛强度之间的相关性。
从表现出不同程度牙髓痛的 60 名患者中选择了 55 名患者进行本研究，其中 7 名患者被排除/放弃，留下了 55 名患者进行评估。研究纳入下颌磨牙伴有症状性不可复性牙髓炎且无根尖病变的患者。从患者中获得 5ml 未刺激唾液，然后给予局部麻醉。随后进行根管治疗，并记录术前和术后的疼痛评分。此外，在紧急根管治疗后收集唾液样本并进行唾液生化分析。采用 IBM.SPSS 统计软件 23.0 评估获得的数据。
与术前相比，术后疼痛评分（P<0.001）和 SAA 水平（P<0.001）均显著下降。在接受紧急根管治疗的患者中，SAA 水平与疼痛评分之间存在强烈的正相关关系，在两个时间间隔（即术前（P<0.001）和术后（P<0.001））均如此。
本初步研究结果表明，在接受紧急根管治疗的患者中，疼痛评分和 SAA 水平之间存在强烈的相关性。
