Costa Ferreira Fernanda d'Araujo, Saad Eduardo B
Center for Atrial Fibrillation - Hospital Pró Cardíaco, Rio de Janeiro, Brazil.
J Atr Fibrillation. 2008 Dec 1;1(4):38. doi: 10.4022/jafib.38. eCollection 2008 Dec.
Atrial fibrillation is associated with thromboembolic events that may cause important impairment on quality of life. Pulmonary vein isolation is the treatment of choice in cases that are refractory to medical therapy. Once sheaths and catheters are manipulated inside the left atrium, anticoagulation with heparin must be used during the procedure to protect patients from thromboembolic phenomena. Different strategies of anticoagulation are used at different centers. This review summarizes the pathophysiology of thrombus formation in the left atrium, defines which patients are under high risk and describes the main strategies used for anticoagulation.
心房颤动与血栓栓塞事件相关，这些事件可能对生活质量造成严重损害。对于药物治疗无效的病例，肺静脉隔离是首选治疗方法。一旦鞘管和导管在左心房内操作，术中必须使用肝素进行抗凝，以保护患者免受血栓栓塞现象的影响。不同的中心采用不同的抗凝策略。本综述总结了左心房血栓形成的病理生理学，确定了哪些患者处于高风险状态，并描述了主要的抗凝策略。
