Deneke Thomas, Schade Anja, Krug Joachim, Stahl Karsten, Atilla Szollosi Geza, In Shin Dong, Nino Schukro Clemens, El Tarahony Mohamed, Murillo Enrique, Aram Semko, Robhirt Gabriele, Lawo Thomas, Mugge Andreas, Grewe Peter H, Kerber Sebastian
Heart Center Bad Neustadt, Clinic for interventional Electrophysiology, Bad Neustadt/Saale, GER.
Ruhr-University Bochum, Bochum, GER.
J Atr Fibrillation. 2012 Feb 2;4(5):498. doi: 10.4022/jafib.498. eCollection 2012 Feb-Mar.
Catheter ablation of atrial fibrillation (AF) has been increasingly used to treat symptomatic patients.Within the last years a growing interest in ablation of persistent AF forms has evolved.Factors that may influence outcome of these procedures to treat persistent AF may be patient-specific (pre-procedural),procedure-related or may involve different post-ablation followup strategies. In this review potential factors predicting recurrence of AF after ablation of persistent AF have been evaluated.In essence, data is limited mostly due to incongruent definitions of persistent AF.Left atrial dimensions, duration of continuous AF and AF cycle length may be patient-specific predictors of outcome. Intra-procedural parameters involved in recurrence prediction may be extent of ablation (effective pulmonary vein isolation appears mandatory) and termination of AF during ablation. Timing and number of cardioversion if persistent AF recurs may predict outcome, as well. Many studies have identified strators for higher recurrence rates in rather small patient groups and need to be further evaluated in larger patient collectives.
导管消融术已越来越多地用于治疗有症状的心房颤动(AF)患者。在过去几年中,人们对持续性房颤形式的消融越来越感兴趣。可能影响这些治疗持续性房颤手术结果的因素可能是患者特异性的(术前)、与手术相关的,或可能涉及不同的消融后随访策略。在本综述中,对预测持续性房颤消融术后房颤复发的潜在因素进行了评估。本质上,由于持续性房颤的定义不一致,数据大多有限。左心房大小、持续性房颤持续时间和房颤周期长度可能是患者特异性的预后预测因素。参与复发预测的术中参数可能是消融范围(有效的肺静脉隔离似乎是必需的)和消融期间房颤的终止。如果持续性房颤复发,复律的时机和次数也可能预测预后。许多研究已经在相当小的患者群体中确定了复发率较高的预测因素,需要在更大的患者群体中进一步评估。