Ganga Harsha V, Kolla Nandini, Zimmerman M Bridget, Miller Wayne L
Division of Cardiology, Hartford Hospital, Hartford, CT.
Department of Internal Medicine, Abington Memorial Hospital, Willow Grove, PA.
J Atr Fibrillation. 2012 Apr 14;4(6):515. doi: 10.4022/jafib.515. eCollection 2012 Apr-May.
To determine if a clinically significant relation exists between chronic anemia and the new-onset atrial fibrillation (AF) in the elderly population from a community setting. This is a single center community-based retrospective cohort study. Data were collected on 3867 patients over the age of 65 years presenting to the Mercy Medical Center in the year 2006. Patients without AF were divided into anemic and non-anemic groups and were followed over the next two years for the new-onset AF. Chronic anemia was defined as hemoglobin level less than 13g/dl in males and less than 12g/dl in females from two laboratory values checked at least 4 months apart. Of the 2873 patients without AF, 2382 (83%) patients were non-anemic. 491 patients were anemic. New-onset AF was found in 7.5 % of the anemic patients and 5.5% of the non-anemic patients. After the adjustment for comorbid conditions, chronic anemia is not associated with new-onset AF (p=0.922). In this study cohort of elderly community-based patients, chronic anemia is not associated with the new-onset AF.
为了确定在社区环境中的老年人群中，慢性贫血与新发心房颤动（AF）之间是否存在具有临床意义的关联。这是一项基于社区的单中心回顾性队列研究。收集了2006年到 Mercy 医疗中心就诊的3867名65岁以上患者的数据。无房颤的患者被分为贫血组和非贫血组，并在接下来的两年中随访新发房颤情况。慢性贫血定义为两次至少间隔4个月检查的实验室值中，男性血红蛋白水平低于13g/dl，女性低于12g/dl。在2873名无房颤的患者中，2382名（83%）患者无贫血，491名患者贫血。贫血患者中新发房颤的发生率为7.5%，非贫血患者为5.5%。在对合并症进行调整后，慢性贫血与新发房颤无关（p = 0.922）。在这个基于社区的老年患者研究队列中，慢性贫血与新发房颤无关。
