医生是否应继续向心房颤动患者推荐鱼油？
Should Physicians Continue to Recommend Fish Oil for Patients with Atrial Fibrillation?
作者信息
Robinson Victoria M, Kowey Peter R
机构信息
The University of Edinburgh, Edinburgh, United Kingdom.
Lankenau Medical Center and Institute for Medical Research, and the Thomas Jefferson University, Philadelphia, United States of America.
出版信息
J Atr Fibrillation. 2012 Oct 6;5(3):593. doi: 10.4022/jafib.593. eCollection 2012 Oct-Nov.
Abstract
Many physicians recommend the use of fish oil or omega-3 polyunsaturated fatty acids (n-3 PUFA) in atrial fibrillation (AF) patients. N-3 PUFA have demonstrated anti-fibrillatory properties in several animal studies, however, data regarding their efficacy in preventing AF in humans have been mixed. This article critically reviews studies that have investigated the use of n-3 PUFA for the secondary prevention of paroxysmal and persistent AF and the primary prevention of post-operative AF. We conclude that n-3 PUFA should no longer be recommended for use in any of these AF subtypes until more data are available.
摘要
许多医生建议心房颤动（AF）患者使用鱼油或ω-3多不饱和脂肪酸（n-3 PUFA）。在多项动物研究中，n-3 PUFA已显示出抗纤颤特性，然而，关于其在预防人类房颤方面疗效的数据却参差不齐。本文对研究n-3 PUFA用于阵发性和持续性房颤二级预防以及术后房颤一级预防的研究进行了批判性综述。我们得出结论，在获得更多数据之前，不应再推荐n-3 PUFA用于任何这些房颤亚型。
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